Literature DB >> 28886376

Converting Cold into Hot Tumors by Combining Immunotherapies.

John B A G Haanen1.   

Abstract

In a small phase Ib study in this issue of Cell, Ribas et al. report that the combination of intralesional injection of a modified human herpes simplex virus and systemic anti-PD-1 treatment resulted in a 62% response rate in patients with metastatic melanoma, accompanied by enhanced T cell infiltration in virus-injected lesions.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID: 28886376     DOI: 10.1016/j.cell.2017.08.031

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  67 in total

1.  Long-term response to ipilimumab after nivolumab failure in a case of anorectal melanoma with an intermediate tumor mutation burden and negative for PD-L1 expression.

Authors:  Hitomi Sakai; Masayuki Takeda; Kazuko Sakai; Kazuto Nishio; Kazuhiko Nakagawa
Journal:  Mol Clin Oncol       Date:  2020-05-21

Review 2.  Nanotechnology and Immunotherapy in Ovarian Cancer: Tracing New Landscapes.

Authors:  Bruna Corradetti; Simone Pisano; Robert Steven Conlan; Mauro Ferrari
Journal:  J Pharmacol Exp Ther       Date:  2019-02-08       Impact factor: 4.030

3.  Targeting a scavenger receptor on tumor-associated macrophages activates tumor cell killing by natural killer cells.

Authors:  Silke Eisinger; Dhifaf Sarhan; Vanessa F Boura; Itziar Ibarlucea-Benitez; Sofia Tyystjärvi; Ganna Oliynyk; Marie Arsenian-Henriksson; David Lane; Stina L Wikström; Rolf Kiessling; Tommaso Virgilio; Santiago F Gonzalez; Dagmara Kaczynska; Shigeaki Kanatani; Evangelia Daskalaki; Craig E Wheelock; Saikiran Sedimbi; Benedict J Chambers; Jeffrey V Ravetch; Mikael C I Karlsson
Journal:  Proc Natl Acad Sci U S A       Date:  2020-11-23       Impact factor: 11.205

Review 4.  The Course of Immune Stimulation by Photodynamic Therapy: Bridging Fundamentals of Photochemically Induced Immunogenic Cell Death to the Enrichment of T-Cell Repertoire.

Authors:  Shubhankar Nath; Girgis Obaid; Tayyaba Hasan
Journal:  Photochem Photobiol       Date:  2019-11-10       Impact factor: 3.421

5.  Neutrophil content predicts lymphocyte depletion and anti-PD1 treatment failure in NSCLC.

Authors:  Julia Kargl; Xiaodong Zhu; Huajia Zhang; Grace H Y Yang; Travis J Friesen; Melissa Shipley; Dean Y Maeda; John A Zebala; Jill McKay-Fleisch; Gavin Meredith; Afshin Mashadi-Hossein; Christina Baik; Robert H Pierce; Mary W Redman; Jeffrey C Thompson; Steven M Albelda; Hamid Bolouri; A McGarry Houghton
Journal:  JCI Insight       Date:  2019-12-19

Review 6.  Head and Neck Cancer Immunotherapy beyond the Checkpoint Blockade.

Authors:  B R Heath; N L Michmerhuizen; C R Donnelly; K Sansanaphongpricha; D Sun; J C Brenner; Y L Lei
Journal:  J Dent Res       Date:  2019-07-24       Impact factor: 6.116

7.  Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice.

Authors:  Ying Wang; Lijing Su; Matthew D Morin; Brian T Jones; Yuto Mifune; Hexin Shi; Kuan-Wen Wang; Xiaoming Zhan; Aijie Liu; Jianhui Wang; Xiaohong Li; Miao Tang; Sara Ludwig; Sara Hildebrand; Kejin Zhou; Daniel J Siegwart; Eva Marie Y Moresco; Hong Zhang; Dale L Boger; Bruce Beutler
Journal:  Proc Natl Acad Sci U S A       Date:  2018-08-27       Impact factor: 11.205

8.  Immune Modulation by Telomerase-Specific Oncolytic Adenovirus Synergistically Enhances Antitumor Efficacy with Anti-PD1 Antibody.

Authors:  Nobuhiko Kanaya; Shinji Kuroda; Yoshihiko Kakiuchi; Kento Kumon; Tomoko Tsumura; Masashi Hashimoto; Toshiaki Morihiro; Tetsushi Kubota; Katsuyuki Aoyama; Satoru Kikuchi; Masahiko Nishizaki; Shunsuke Kagawa; Hiroshi Tazawa; Hiroyuki Mizuguchi; Yasuo Urata; Toshiyoshi Fujiwara
Journal:  Mol Ther       Date:  2020-01-10       Impact factor: 11.454

9.  Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses.

Authors:  Fan Huang; Christophe Gonçalves; Margarita Bartish; Joelle Rémy-Sarrazin; Mark E Issa; Brendan Cordeiro; Qianyu Guo; Audrey Emond; Mikhael Attias; William Yang; Dany Plourde; Jie Su; Marina Godoy Gimeno; Yao Zhan; Alba Galán; Tomasz Rzymski; Milena Mazan; Magdalena Masiejczyk; Jacek Faber; Elie Khoury; Alexandre Benoit; Natascha Gagnon; David Dankort; Fabrice Journe; Ghanem E Ghanem; Connie M Krawczyk; H Uri Saragovi; Ciriaco A Piccirillo; Nahum Sonenberg; Ivan Topisirovic; Christopher E Rudd; Wilson H Miller; Sonia V Del Rincón
Journal:  J Clin Invest       Date:  2021-04-15       Impact factor: 14.808

10.  Ovarian Cancer: Therapeutic Strategies to Overcome Immune Suppression.

Authors:  Maureen L Drakes; Patrick J Stiff
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

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