Md Dilshad Manzar1, Mohammed Salahuddin2, Tarekegn Tesfaye Maru2, Tegene Legese Dadi3, Mathewos Geneto Abiche1, Dejene Derseh Abateneh1, Seithikurippu R Pandi-Perumal4, Ahmed S Bahammam5,6. 1. Department of Biomedical Sciences, College of Health Sciences, Mizan-Tepi University (Mizan Campus), Mizan-Aman, Ethiopia. 2. Department of Pharmacy, College of Health Sciences, Mizan-Tepi University (Mizan Campus), Mizan-Aman, Ethiopia. 3. Department of Public Health, College of Health Sciences, Mizan-Tepi University (Mizan Campus), Mizan-Aman, Ethiopia. 4. Somnogen Canada Inc, College Street, Toronto, ON, Canada. 5. The University Sleep Disorders Center, College of Medicine, King Saud University, Box 225503, Riyadh, 11324, Saudi Arabia. ashammam2@gmail.com. 6. National Plan for Science and Technology, College of Medicine, King Saud University, Riyadh, Saudi Arabia. ashammam2@gmail.com.
Abstract
PURPOSE: The relationship between sleep disturbances and substance use can have harmful effects. Evidence shows widespread use of substances, including khat, in the Ethiopian population. However, to the best of our knowledge, no study has investigated the sleep correlates of substance use in community-dwelling Ethiopian adults. MATERIALS AND METHODS: A cross-sectional study using simple random sampling was performed on community-dwelling adults (n = 371, age = 25.5 ± 5.7 years, body mass index = 22.0 ± 2.2 kg/m2) in Mizan-Aman, Ethiopia. Dichotomized sleep measures (sleep quality and sleep latency) assessed by the Pittsburgh Sleep Quality Index (PSQI) were used in association analysis using binary logistic regression with substance use (khat, smoking, and alcohol). RESULT: Sleep latency was associated with khat chewing (adjusted odds ratio (AOR) = 2.8, 95% confidence interval (CI) 1.7-4.4) and tobacco smoking (AOR = 2.1, 95% CI 1.4-3.0). Sleep quality was associated with khat chewing (AOR = 3.1, 95% CI 1.8-5.2), tobacco smoking (AOR = 1.7, 95% CI 1.2-2.5), and alcohol intake (AOR = 1.9, 95% CI 1.1-3.1). CONCLUSION: Sleep correlates of substance use were found in community-dwelling Ethiopians. These findings may aid in the development of targeted strategies to manage substance use-related sleep disturbances.
PURPOSE: The relationship between sleep disturbances and substance use can have harmful effects. Evidence shows widespread use of substances, including khat, in the Ethiopian population. However, to the best of our knowledge, no study has investigated the sleep correlates of substance use in community-dwelling Ethiopian adults. MATERIALS AND METHODS: A cross-sectional study using simple random sampling was performed on community-dwelling adults (n = 371, age = 25.5 ± 5.7 years, body mass index = 22.0 ± 2.2 kg/m2) in Mizan-Aman, Ethiopia. Dichotomized sleep measures (sleep quality and sleep latency) assessed by the Pittsburgh Sleep Quality Index (PSQI) were used in association analysis using binary logistic regression with substance use (khat, smoking, and alcohol). RESULT: Sleep latency was associated with khat chewing (adjusted odds ratio (AOR) = 2.8, 95% confidence interval (CI) 1.7-4.4) and tobacco smoking (AOR = 2.1, 95% CI 1.4-3.0). Sleep quality was associated with khat chewing (AOR = 3.1, 95% CI 1.8-5.2), tobacco smoking (AOR = 1.7, 95% CI 1.2-2.5), and alcohol intake (AOR = 1.9, 95% CI 1.1-3.1). CONCLUSION: Sleep correlates of substance use were found in community-dwelling Ethiopians. These findings may aid in the development of targeted strategies to manage substance use-related sleep disturbances.
Authors: Mohammed Salahuddin; Md Dilshad Manzar; Hamid Yimam Hassen; Aleem Unissa; Unaise Abdul Hameed; David Warren Spence; Seithikurippu R Pandi-Perumal Journal: HIV AIDS (Auckl) Date: 2020-10-13
Authors: Md Dilshad Manzar; Ahmad H Alghadir; Masood Khan; Mohammed Salahuddin; Hamid Yimam Hassen; Ahmed M Almansour; Dejen Nureye; Eyob Tekalign; Showkat Ahmad Shah; Seithikurippu R Pandi-Perumal; Ahmed S Bahammam Journal: Front Psychiatry Date: 2022-05-10 Impact factor: 5.435
Authors: Md Dilshad Manzar; Mohammed Salahuddin; Tarekegn Tesfaye Maru; Ahmad Alghadir; Shahnawaz Anwer; Ahmed S Bahammam; Seithikurippu R Pandi-Perumal Journal: Health Qual Life Outcomes Date: 2018-03-13 Impact factor: 3.186
Authors: Md Dilshad Manzar; Mohammed Salahuddin; Majed Alamri; Tarekegn Tesfaye Maru; Seithikurippu R Pandi-Perumal; Ahmed S Bahammam Journal: Ann Thorac Med Date: 2018 Oct-Dec Impact factor: 2.219
Authors: Md Dilshad Manzar; Mohammed Salahuddin; Majed Alamri; Abdulrhman Albougami; Mohammad Yunus Ali Khan; Dejen Nureye; D Warren Spence; Seithikurippu R Pandi-Perumal Journal: Health Qual Life Outcomes Date: 2019-02-07 Impact factor: 3.186
Authors: Naznin Sultana; Md Asaduzzaman; Firoj Al Mamun; Ismail Hosen; Qian Yu; Amir H Pakpour; David Gozal; Mohammed A Mamun Journal: Nat Sci Sleep Date: 2021-05-26