Literature DB >> 28882939

Wasp sting induced STEMI with complete coronary artery occlusion: a case of Kounis syndrome.

Benjamin Cross1, Tawfiqur Rahman Choudhury2, Mark Hindle3, Gavin Galasko2.   

Abstract

A 45-year-old previously healthy man with minimal coronary artery disease on imaging presented with an acute MI after sustaining a wasp sting following previous non-eventful exposures throughout his life. This is the first case of Kounis syndrome with optical coherence tomography imaging and proven IgE wasp venom hypersensitivity. The Hymenoptera venom is composed of allergenic proteins and vasoactive amines which are responsible for venom toxicity. This patient also has a history of atopy giving a predisposition for developing IgE-mediated allergic reactions. Hymenoptera stings can be severe in atopic individuals and anaphylaxis may ensue. However, it is a rare cause of myocardial infarction (MI) (Kounis syndrome). Multiple wasp stings in the past may have contributed to sensitisation. Kounis syndrome is a rare clinical manifestation which should remain in the minds of physicians, especially with younger patients with no history of ischaemic heart disease or few risk factors. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  cardiovascular medicine; clinical diagnostic tests; immunology; ischaemic heart disease

Mesh:

Substances:

Year:  2017        PMID: 28882939      PMCID: PMC5589030          DOI: 10.1136/bcr-2017-221256

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  15 in total

1.  Type I variant of Kounis syndrome secondary to wasp sting.

Authors:  Erminia Ridolo; Elisa Olivieri; Marcello Montagni; Angelo Rolli; Gianenrico E Senna
Journal:  Ann Allergy Asthma Immunol       Date:  2012-05-25       Impact factor: 6.347

Review 2.  Key recommendations and evidence from the NICE guideline for the acute management of ST-segment-elevation myocardial infarction.

Authors:  Martin Harker; Serena Carville; Robert Henderson; Huon Gray
Journal:  Heart       Date:  2013-09-05       Impact factor: 5.994

Review 3.  Treatment of Kounis syndrome.

Authors:  Cihan Cevik; Kenneth Nugent; Goutam P Shome; Nicholas G Kounis
Journal:  Int J Cardiol       Date:  2010-03-04       Impact factor: 4.164

4.  Prevalence of allergen sensitization, most important allergens and factors associated with atopy in children.

Authors:  Raquel Prudente de Carvalho Baldaçara; Maria de Fátima Marcelos Fernandes; Leonardo Baldaçara; Wilson Tartuce Aun; João Ferreira de Mello; Mario Cesar Pires
Journal:  Sao Paulo Med J       Date:  2013       Impact factor: 1.044

Review 5.  Coronary hypersensitivity disorder: the Kounis syndrome.

Authors:  Nicholas G Kounis
Journal:  Clin Ther       Date:  2013-03-13       Impact factor: 3.393

Review 6.  Insect sting anaphylaxis.

Authors:  David B K Golden
Journal:  Immunol Allergy Clin North Am       Date:  2007-05       Impact factor: 3.479

Review 7.  Histamine-induced coronary artery spasm: the concept of allergic angina.

Authors:  N G Kounis; G M Zavras
Journal:  Br J Clin Pract       Date:  1991

Review 8.  Allergic reactions to insect stings and bites.

Authors:  John E Moffitt
Journal:  South Med J       Date:  2003-11       Impact factor: 0.954

9.  ST elevation myocardial infarction with no structural lesions after a wasp sting.

Authors:  Sofiene Rekik; Stephane Andrieu; Falah Aboukhoudir; Pierre Barnay; Gonzalo Quaino; Michel Pansieri; Jean Lou Hirsch
Journal:  J Emerg Med       Date:  2009-03-27       Impact factor: 1.484

10.  Kounis syndrome presenting as very late stent thrombosis in an everolimus-eluting stent following wasp stings.

Authors:  Jung Hwa Min; Min-Ho Kang
Journal:  Korean Circ J       Date:  2013-08-31       Impact factor: 3.243

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  3 in total

1.  Investigation on the Effect of Age and Gender on Hypersensitivity Reactions due to Allergens Injection in Iraqi Population.

Authors:  Lateef I Nadhim
Journal:  Arch Razi Inst       Date:  2022-02-28

2.  Development and internal validation of a Wasp Sting Severity Score to assess severity and indicate blood purification in persons with Asian wasp stings.

Authors:  Yong Liu; Hongmei Shu; Youlin Long; Xiaoqin Nie; Hongfu Tang; Lang Tu; Hao Zhang; Gang Qiu; Daihua He; Qiang Huang; Qi Zhang; Shuang Qing; Donglin Xu; Hongtao Xia
Journal:  Clin Kidney J       Date:  2021-10-07

Review 3.  Kounis syndrome: from an unexpected case in the Emergency Room to a review of the literature.

Authors:  Erika Poggiali; Irene Benedetti; Valeria Vertemati; Luca Rossi; Alberto Monello; Manuela Giovini; Andrea Magnacavallo; Andrea Vercelli
Journal:  Acta Biomed       Date:  2022-03-14
  3 in total

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