Yasuko Fujita1,2, Mitsuo Kishimoto3, Osamu Dohi4, Kazuhiro Kamada4, Atsushi Majima4, Reiko Kimura-Tsuchiya4,5, Nobuaki Yagi4,6, Hideyuki Konishi4, Yuji Naito4, Yoshinori Harada7, Hideo Tanaka7, Eiichi Konishi3, Tamotsu Sugai8, Akio Yanagisawa3,9. 1. Department of Molecular Diagnostic Pathology, School of Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka, 020-0023, Japan. fujitaya@iwate-med.ac.jp. 2. Department of Pathology and Cell Regulation, Kyoto Prefectural University of Medicine, Kyoto, Japan. fujitaya@iwate-med.ac.jp. 3. Department of Surgical Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan. 4. Department of Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Kyoto, Japan. 5. Department of Medical Oncology, Fukushima Medical University, Fukushima, Japan. 6. Department of Gastroenterology, Murakami Memorial Hospital, Asahi University, Gifu, Japan. 7. Department of Pathology and Cell Regulation, Kyoto Prefectural University of Medicine, Kyoto, Japan. 8. Department of Molecular Diagnostic Pathology, School of Medicine, Iwate Medical University, 19-1 Uchimaru, Morioka, 020-0023, Japan. 9. Department of Pathology, Kyoto Daiichi Red Cross Hospital, Kyoto, Japan.
Abstract
BACKGROUND: Endoscopic findings have now become nearly as detailed as histopathological findings. Thus, one-to-one correspondence and precise feedback of histopathological findings is very desirable but may be very difficult to accomplish. We describe a systematic process called the Kyoto One-to-One Correspondence Method (the KOTO Method) that allows detailed adjustments of endoscopic findings to match histopathological findings. METHODS AND RESULTS: By comparing endoscopic and stereoscopic images of the gastric mucosa, we could obtain one-to-one correspondence between endoscopic images and equivalent histology in 44 of 47 fields. CONCLUSIONS: The histological structure of gastric cancers of the same histological subtype may not be similar. One-to-one correspondence between endoscopic images and gastric mucosal histology (histopathology-oriented correspondence) will improve endoscopic diagnosis and provide more useful information for pathological diagnosis.
BACKGROUND: Endoscopic findings have now become nearly as detailed as histopathological findings. Thus, one-to-one correspondence and precise feedback of histopathological findings is very desirable but may be very difficult to accomplish. We describe a systematic process called the Kyoto One-to-One Correspondence Method (the KOTO Method) that allows detailed adjustments of endoscopic findings to match histopathological findings. METHODS AND RESULTS: By comparing endoscopic and stereoscopic images of the gastric mucosa, we could obtain one-to-one correspondence between endoscopic images and equivalent histology in 44 of 47 fields. CONCLUSIONS: The histological structure of gastric cancers of the same histological subtype may not be similar. One-to-one correspondence between endoscopic images and gastric mucosal histology (histopathology-oriented correspondence) will improve endoscopic diagnosis and provide more useful information for pathological diagnosis.