Literature DB >> 28872215

Alzheimer's disease.

C A Lane1, J Hardy2, J M Schott1.   

Abstract

Alzheimer's disease, the commonest cause of dementia, is a growing global health concern with huge implications for individuals and society. In this review, current understanding of the epidemiology, genetics, pathology and pathogenesis of Alzheimer's disease is outlined, before its clinical presentation and current treatment strategies are discussed. Finally, the review discusses how our enhanced understanding of Alzheimer pathogenesis, including the recognition of a protracted preclinical phase, is informing new therapeutic strategies with the aim of moving from treatment to prevention.
© 2017 EAN.

Entities:  

Keywords:  Alzheimer's disease; epidemiology; genetics; pathogenesis; pathology; treatment

Mesh：

Year:  2017        PMID： 28872215     DOI： 10.1111/ene.13439

Source DB:  PubMed          Journal:  Eur J Neurol        ISSN： 1351-5101            Impact factor:   6.089


  440 in total

1.  To Keto or Not to Keto? A Systematic Review of Randomized Controlled Trials Assessing the Effects of Ketogenic Therapy on Alzheimer Disease.

Authors:  Maria G Grammatikopoulou; Dimitrios G Goulis; Konstantinos Gkiouras; Xenophon Theodoridis; Kalliopi K Gkouskou; Athanasios Evangeliou; Efthimis Dardiotis; Dimitrios P Bogdanos
Journal:  Adv Nutr       Date:  2020-11-16       Impact factor: 8.701

2.  Therapeutic potential of Allium Sativum against the Aβ(1-40)-induced oxidative stress and mitochondrial dysfunction in the Wistar rats.

Authors:  Neetu Saini; Monika Kadian; Alka Khera; Aanchal Aggarwal; Anil Kumar
Journal:  Am J Neurodegener Dis       Date:  2021-04-15

3.  MG53 attenuates lipopolysaccharide-induced neurotoxicity and neuroinflammation via inhibiting TLR4/NF-κB pathway in vitro and in vivo.

Authors:  Fangxia Guan; Xinkui Zhou; Peng Li; Yaping Wang; Ming Liu; Fangfang Li; Yuanbo Cui; Tuanjie Huang; Minghao Yao; Yanting Zhang; Jianjie Ma; Shanshan Ma
Journal:  Prog Neuropsychopharmacol Biol Psychiatry       Date:  2019-06-29       Impact factor: 5.067

4.  Targeting Iron Dyshomeostasis for Treatment of Neurodegenerative Disorders.

Authors:  Niels Bergsland; Eleonora Tavazzi; Ferdinand Schweser; Dejan Jakimovski; Jesper Hagemeier; Michael G Dwyer; Robert Zivadinov
Journal:  CNS Drugs       Date:  2019-11       Impact factor: 5.749

Review 5.  Enabling biodegradable functional biomaterials for the management of neurological disorders.

Authors:  Dingying Shan; Chuying Ma; Jian Yang
Journal:  Adv Drug Deliv Rev       Date:  2019-06-20       Impact factor: 15.470

6.  The Insomnia Plague in Fictional Macondo.

Authors:  Alejandro Velásquez-Torres; Andrés Díaz-Forero; Claudia Talero-Gutiérrez
Journal:  Perm J       Date:  2020

7.  Resveratrol Induces Brain Resilience Against Alzheimer Neurodegeneration Through Proteostasis Enhancement.

Authors:  Rubén Corpas; Christian Griñán-Ferré; Eduard Rodríguez-Farré; Mercè Pallàs; Coral Sanfeliu
Journal:  Mol Neurobiol       Date:  2018-06-13       Impact factor: 5.590

8.  Physical exercise prevents amyloid β1-40-induced disturbances in NLRP3 inflammasome pathway in the hippocampus of mice.

Authors:  Julia M Rosa; Anderson Camargo; Ingrid A V Wolin; Manuella P Kaster; Ana Lúcia S Rodrigues
Journal:  Metab Brain Dis       Date:  2020-11-19       Impact factor: 3.584

9.  Association Between Leptin, Cognition, and Structural Brain Measures Among "Early" Middle-Aged Adults: Results from the Framingham Heart Study Third Generation Cohort.

Authors:  Victoria Sanborn; Sarah R Preis; Alvin Ang; Sherral Devine; Jesse Mez; Charles DeCarli; Rhoda Au; Michael L Alosco; John Gunstad
Journal:  J Alzheimers Dis       Date:  2020       Impact factor: 4.472

10.  The preventive efficacy of vitamin B supplements on the cognitive decline of elderly adults: a systematic review and meta-analysis.

Authors:  Shufeng Li; Yuchen Guo; Jie Men; Hanlin Fu; Ting Xu
Journal:  BMC Geriatr       Date:  2021-06-16       Impact factor: 3.921
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