Jesper Roed Sorensen1, Torquil Watt2, Per Cramon2, Helle Døssing1, Laszlo Hegedüs3, Steen Joop Bonnema3, Christian Godballe1,4. 1. Department of ORL Head & Neck Surgery, Odense University Hospital, Odense, Denmark. 2. Department of Medical Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark. 3. Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark. 4. OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark.
Abstract
BACKGROUND: Using the thoroughly validated Thyroid-Related Quality-of-Life Patient-Reported Outcome (ThyPRO) questionnaire, the purpose of this study was to investigate changes in disease-specific quality of life (QOL) after surgical treatment in patients with benign nontoxic multinodular goiters. METHOD: Patients with goiters scheduled for thyroid surgery (n = 106) and individuals from the general population (n = 739) were studied. The ThyPRO data before, 3 months, and 6 months after surgery were compared with normative scores from the general population using a linear mixed model and t tests. RESULTS: Before surgery, patients with goiters experienced poorer scores on all scales compared to the general population. After surgery, moderate to large improvements were seen in goiter symptoms, tiredness, anxiety, and overall QOL. After surgery, all scales returned to values equal to the general population. The degree of anxiety was, in fact, lower than in the general population. CONCLUSION: Thyroid surgery leads to significant benefit among patients with benign nontoxic goiters by restoring QOL equal to that in the general population.
BACKGROUND: Using the thoroughly validated Thyroid-Related Quality-of-Life Patient-Reported Outcome (ThyPRO) questionnaire, the purpose of this study was to investigate changes in disease-specific quality of life (QOL) after surgical treatment in patients with benign nontoxic multinodular goiters. METHOD:Patients with goiters scheduled for thyroid surgery (n = 106) and individuals from the general population (n = 739) were studied. The ThyPRO data before, 3 months, and 6 months after surgery were compared with normative scores from the general population using a linear mixed model and t tests. RESULTS: Before surgery, patients with goiters experienced poorer scores on all scales compared to the general population. After surgery, moderate to large improvements were seen in goiter symptoms, tiredness, anxiety, and overall QOL. After surgery, all scales returned to values equal to the general population. The degree of anxiety was, in fact, lower than in the general population. CONCLUSION: Thyroid surgery leads to significant benefit among patients with benign nontoxic goiters by restoring QOL equal to that in the general population.
Authors: Brendan M Finnerty; Katherine D Gray; Timothy M Ullmann; Rasa Zarnegar; Thomas J Fahey; Toni Beninato Journal: World J Surg Date: 2020-06 Impact factor: 3.352
Authors: Natalia Chaves; M Juanita Rodriguez; Jordan M Broekhuis; Hao Wei Chen; Paul A Bain; Benjamin C James Journal: World J Surg Date: 2022-01-24 Impact factor: 3.352