Amar M Salam1, Kadhim Sulaiman2, Alawi A Alsheikh-Ali3,4, Rajvir Singh5, Nidal Asaad1, Awad Al-Qahtani1, Imtiaz Salim1, Khalid F AlHabib6, Ibrahim Al-Zakwani7, Mohammed Al-Jarallah8, Wael AlMahmeed9, Bassam Bulbanat8, Mustafa Ridha10, Nooshin Bazargani11, Haitham Amin12, Ahmed Al-Motarreb13, Husam Al Faleh14, Hanan Albackr6, Prashanth Panduranga2, Abdulla Shehab15, Jassim Al Suwaidi1,16. 1. a Adult Cardiology , Hamad Medical Corporation , Doha , Qatar. 2. b Department of Cardiology , Royal Hospital , Muscat , Oman. 3. c College of Medicine , Mohammed Bin Rashid University of Medicine and Health Sciences , Dubai , United Arab Emirates. 4. d Institute of Cardiac Sciences , Sheikh Khalifa Medical City , Abu Dhabi , United Arab Emirates. 5. e Biostatistics Section, Cardiovascular Research , Heart Hospital, Hamad Medical Corporation , Doha , Qatar. 6. f Department of Cardiac Sciences , King Fahad Cardiac Center, King Saud University , Riyadh , Saudi Arabia. 7. g College of Medicine & Health Sciences, Department of Pharmacology & Clinical Pharmacy , Sultan Qaboos University, and Gulf Health Research , Oman. 8. h Department of Cardiology , Sabah Al-Ahmed Cardiac Center , Kuwait. 9. i Cleveland Clinic , Abdu Dhabi , United Arab Emirates. 10. j Department of Cardiology , Adan Hospital , Kuwait. 11. k Department of Cardiology , Dubai hospital , Dubai , United Arab Emirates. 12. l Department of Cardiology , Mohammed Bin Khalifa Cardiac Center , Manamah , Bahrain. 13. m Department of Cardiology, Faculty of Medicine , Sana'a University , Sana'a , Yemen. 14. n Department of Cardiology and Cardiovascular Surgery , Security Forces Hospital , Riyadh , Saudi Arabia. 15. o Internal Medicine Department , College of Medicine and Health Sciences (CMHS), UAE University , United Arab Emirates. 16. p Qatar Cardiovascular Research Center , Doha , Qatar.
Abstract
BACKGROUND: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic dimensions. This study examined the effects of fasting in patients with acute heart failure (AHF) using data from a large multi-center heart failure registry. METHODS AND RESULTS: Data were derived from Gulf CARE (Gulf aCute heArt failuRe rEgistry), a prospective multi-center study of consecutive patients hospitalized with AHF during February-November 2012. The study included 4,157 patients, of which 306 (7.4%) were hospitalized with AHF in the fasting month of Ramadan, while 3,851 patients (92.6%) were hospitalized in other days. Clinical characteristics, precipitating factors, management, and outcome were compared among the two groups. Patients admitted during Ramadan had significantly lower prevalence of symptoms and signs of volume overload compared to patients hospitalized in other months. Atrial arrhythmias were significantly less frequent and cholesterol levels were significantly lower in Ramadan. Hospitalization in Ramadan was not independently associated with increased immediate or 1-year mortality. CONCLUSIONS: The current study represents the largest evaluation of the effects of fasting on AHF. It reports an improved volume status in fasting patients. There were also favorable effects on atrial arrhythmia and total cholesterol and no effects on immediate or long-term outcomes.
BACKGROUND: Fasting during the month of Ramadan is practiced by over 1.5 billion Muslims worldwide. It remains unclear, however, how this change in lifestyle affects heart failure, a condition that has reached epidemic dimensions. This study examined the effects of fasting in patients with acute heart failure (AHF) using data from a large multi-center heart failure registry. METHODS AND RESULTS: Data were derived from Gulf CARE (Gulf aCute heArt failuRe rEgistry), a prospective multi-center study of consecutive patients hospitalized with AHF during February-November 2012. The study included 4,157 patients, of which 306 (7.4%) were hospitalized with AHF in the fasting month of Ramadan, while 3,851 patients (92.6%) were hospitalized in other days. Clinical characteristics, precipitating factors, management, and outcome were compared among the two groups. Patients admitted during Ramadan had significantly lower prevalence of symptoms and signs of volume overload compared to patients hospitalized in other months. Atrial arrhythmias were significantly less frequent and cholesterol levels were significantly lower in Ramadan. Hospitalization in Ramadan was not independently associated with increased immediate or 1-year mortality. CONCLUSIONS: The current study represents the largest evaluation of the effects of fasting on AHF. It reports an improved volume status in fasting patients. There were also favorable effects on atrial arrhythmia and total cholesterol and no effects on immediate or long-term outcomes.
Authors: Ahmet Taha Alper; Mehmet Kadri Akboğa; Kazım Serhan Özcan; İstemihan Tengiz; Uğur Önsel Türk; Mustafa Yıldız; Mehmet Birhan Yılmaz; Meral Kayıkçıoğlu; Emine Gazi; Aylin Yıldırır Journal: Anatol J Cardiol Date: 2021-05 Impact factor: 1.596
Authors: Liqaa A Raffee; Khaled Z Alawneh; Mohammad Khaled Al Suleiman; Rashid K Ibdah; Sukaina I Rawashdeh; Abdel-Hameed W Al-Mistarehi Journal: Ann Med Surg (Lond) Date: 2020-10-02
Authors: Rami M Abazid; Hassan H Khalaf; Haitham I Sakr; Nora A Altorbak; Habiba S Alenzi; Zaki M Awad; Osama A Smettei; Moataz A Elsanan; Adel M Widyan; Ahmed S Azazy; Hassan W Chamsi-Pasha Journal: Saudi Med J Date: 2018-04 Impact factor: 1.484