Literature DB >> 28871477

[Diagnostics and management of herpes zoster ophthalmicus].

R N Werner1,2, N-I Steinhorst3, A Nast1, U Pleyer4.   

Abstract

Herpes zoster (HZ, shingles) represents the secondary manifestation of an infection with varicellazoster virus (VZV). A reactivation of dormant VZV in the ophthalmic branch of the fifth cranial nerve leads to ophthalmic HZ (HZO). The predominantly older and immune compromised patients often present with eye involvement (approximately 50%) as well as characteristic skin changes. Clinical manifestations include the cornea and conjunctiva but anterior uveitis and (rarely) acute retinal necrosis may also occur. Associated sensory symptoms that range from paresthesia to severe pain may severely affect the quality of life. Particularly in immunocompromised and/or elderly patients, HZO is associated with complicated courses. Systemic antiviral treatment and an adequate pain medication are the mainstay of the recommended management. The present article provides an overview of the contents of the current consensus-based European guidelines on the management of HZ with a specific focus on HZO.

Entities:  

Keywords:  Acute retinal necrosis syndrome; Anterior uveitis; Complications; Guidelines; Shingles

Mesh:

Substances:

Year:  2017        PMID: 28871477     DOI: 10.1007/s00347-017-0562-3

Source DB:  PubMed          Journal:  Ophthalmologe        ISSN: 0941-293X            Impact factor:   1.059


  59 in total

Review 1.  Herpes zoster epidemiology, management, and disease and economic burden in Europe: a multidisciplinary perspective.

Authors:  Robert W Johnson; Marie-José Alvarez-Pasquin; Marc Bijl; Elisabetta Franco; Jacques Gaillat; João G Clara; Marc Labetoulle; Jean-Pierre Michel; Luigi Naldi; Luis S Sanmarti; Thomas Weinke
Journal:  Ther Adv Vaccines       Date:  2015-07

2.  Topical treatment with nerve growth factor for corneal neurotrophic ulcers.

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Journal:  N Engl J Med       Date:  1998-04-23       Impact factor: 91.245

3.  A prospective study of the clinical characteristics of patients with herpes simplex and varicella zoster keratitis, presenting to a New Zealand emergency eye clinic.

Authors:  Elissa M McDonald; Dipika V Patel; Charles N J McGhee
Journal:  Cornea       Date:  2015-03       Impact factor: 2.651

Review 4.  [Diagnostic and therapeutic aspects of herpes virus associated uveitis].

Authors:  U Pleyer; S Winterhalter
Journal:  Klin Monbl Augenheilkd       Date:  2010-05-20       Impact factor: 0.700

5.  Oral acyclovir therapy accelerates pain resolution in patients with herpes zoster: a meta-analysis of placebo-controlled trials.

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Journal:  Clin Infect Dis       Date:  1996-02       Impact factor: 9.079

6.  Once, twice, or three times daily famciclovir compared with aciclovir for the oral treatment of herpes zoster in immunocompetent adults: a randomized, multicenter, double-blind clinical trial.

Authors:  Stephen D Shafran; Stephen K Tyring; Richard Ashton; Jacque Decroix; Chistine Forszpaniak; Alan Wade; Christian Paulet; Daniel Candaele
Journal:  J Clin Virol       Date:  2004-04       Impact factor: 3.168

7.  Observations on the natural history of herpes zoster ophthalmicus.

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Journal:  Curr Eye Res       Date:  1987-01       Impact factor: 2.424

8.  CSF and MRI findings in patients with acute herpes zoster.

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Journal:  Neurology       Date:  1998-11       Impact factor: 9.910

9.  Famciclovir for the treatment of acute herpes zoster: effects on acute disease and postherpetic neuralgia. A randomized, double-blind, placebo-controlled trial. Collaborative Famciclovir Herpes Zoster Study Group.

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Journal:  Ann Intern Med       Date:  1995-07-15       Impact factor: 25.391

10.  European consensus-based (S2k) Guideline on the Management of Herpes Zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 2: Treatment.

Authors:  R N Werner; A F Nikkels; B Marinović; M Schäfer; M Czarnecka-Operacz; A M Agius; Z Bata-Csörgő; J Breuer; G Girolomoni; G E Gross; S Langan; R Lapid-Gortzak; T H Lesser; U Pleyer; J Sellner; G M Verjans; P Wutzler; C Dressler; R Erdmann; S Rosumeck; A Nast
Journal:  J Eur Acad Dermatol Venereol       Date:  2016-11-02       Impact factor: 6.166

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  2 in total

1.  [Anterior viral uveitis : Clinical aspects, diagnostic procedure and treatment options].

Authors:  Matthias Lenglinger; Dominika Pohlmann; Uwe Pleyer
Journal:  Ophthalmologe       Date:  2020-01       Impact factor: 1.059

2.  [Corneal alterations in eyelid diseases].

Authors:  Elisabeth M Messmer
Journal:  Ophthalmologe       Date:  2020-09       Impact factor: 1.059

  2 in total

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