Rachael Glassey1, Moira O'Connor2, Angela Ives3, Christobel Saunders4, Sarah J Hardcastle5. 1. Medical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia. Electronic address: rachael.glassey@research.uwa.edu.au. 2. WA Centre for Cancer & Palliative Care, School of Psychology, Curtin University, Perth, Australia. 3. CaPCREU, Medical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia. 4. Medical School, Faculty of Health and Medical Sciences, The University of Western Australia, Perth, Australia. 5. Health Psychology and Behavioural Medicine Research Group, School of Psychology, Curtin University, Perth, Australia.
Abstract
OBJECTIVE: The objective of this study was to explore the influences on decision-making of younger women (<35) undergoing or considering bilateral prophylactic mastectomy (BPM). METHODS: Qualitative interviews guided by interpretative phenomenological analysis (IPA) were conducted with forty-six women who had a strong family history of breast cancer (BC) who had either undergone (n=26) or were considering (n=20) BPM. Participants were recruited from Australia and New Zealand (NZ) via hospitals, a genetics clinic, a research cohort, a registry and online. RESULTS: Four themes underpinning the influences on decision-making were identified: fear and anxiety, children, personal experiences with BC, health professional's influence. CONCLUSIONS: The decision to undergo BPM for younger women (<35) was multifaceted, however, it appeared that fear and anxiety were the main influence. Younger women appear more anxious than previous research with older women. There appears to be few differences between those with confirmed BRCA1/2 mutations and those with no known mutation and this is clinically significant. PRACTICE IMPLICATIONS: These findings have important practice implications, particularly improving communication of risk statistics, especially to those with no known mutation. Health professionals need to take into account the way younger women perceive information given to them when discussing risk.
OBJECTIVE: The objective of this study was to explore the influences on decision-making of younger women (<35) undergoing or considering bilateral prophylactic mastectomy (BPM). METHODS: Qualitative interviews guided by interpretative phenomenological analysis (IPA) were conducted with forty-six women who had a strong family history of breast cancer (BC) who had either undergone (n=26) or were considering (n=20) BPM. Participants were recruited from Australia and New Zealand (NZ) via hospitals, a genetics clinic, a research cohort, a registry and online. RESULTS: Four themes underpinning the influences on decision-making were identified: fear and anxiety, children, personal experiences with BC, health professional's influence. CONCLUSIONS: The decision to undergo BPM for younger women (<35) was multifaceted, however, it appeared that fear and anxiety were the main influence. Younger women appear more anxious than previous research with older women. There appears to be few differences between those with confirmed BRCA1/2 mutations and those with no known mutation and this is clinically significant. PRACTICE IMPLICATIONS: These findings have important practice implications, particularly improving communication of risk statistics, especially to those with no known mutation. Health professionals need to take into account the way younger women perceive information given to them when discussing risk.
Authors: Oscar J Manrique; Ali Charafeddine; Amjed Abu-Ghname; Joseph Banuelos; Steven R Jacobson; Jorys Martinez-Jorge; Minh-Doan Nguyen; Christin Harless; Nho V Tran; Basel Sharaf; James W Jakub; Tina J Hieken; Amy C Degnim; Judy C Boughey Journal: Medicina (Kaunas) Date: 2019-08-14 Impact factor: 2.430
Authors: Sung Mi Jung; Jai Min Ryu; Hyung Seok Park; Ji Soo Park; Eunyoung Kang; Seeyoun Lee; Han-Byoel Lee; Hyun Jo Youn; Tae-Kyung Yoo; Jisun Kim; Jeong Eon Lee; Sang Ah Han; Dongwon Kim; Sung-Won Kim Journal: J Breast Cancer Date: 2020-12-03 Impact factor: 3.588
Authors: Robin Segerer; Clara Peschel; Ulrike Kämmerer; Sebastian Häussler; Achim Wöckel; Sabine Segerer Journal: Breast Care (Basel) Date: 2019-10-01 Impact factor: 2.860