| Literature DB >> 2886887 |
F László, I Pávó, B Penke, G A Bálint.
Abstract
A study was made of the cytoprotective effects of somatostatin (SRIF) and its 3-6, 5-8, 7-10, 9-12 and 11-14 tetrapeptide fragments on absolute ethanol-induced haemorrhagic erosions in the stomach of rat. The SRIF molecule was found to prevent the gastric erosions induced by ethanol. The 7-10 and 11-14 fragments exhibited similar properties. There are two peaks in the cytoprotective dose-response curves. It is concluded that various fragments of SRIF can also exert cytoprotective effects.Entities:
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Year: 1987 PMID： 2886887 DOI： 10.1016/0024-3205(87)90630-8
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037