Literature DB >> 28868341

Flick the cancer stem cells' switch to turn cancer off.

Christophe Ginestier1, Daniel Birnbaum1, Emmanuelle Charafe-Jauffret1.   

Abstract

Tumors are organized in a cellular hierarchy with a population of cancer stem cell (CSC) driving cancer progression and resistance to treatment. Recently, we identified miR-600 as a bimodal switcher that balances breast CSC-fate from a self-renewing to a differentiation state, with a direct impact on tumor progression.

Entities:  

Keywords:  Breast cancer; Cancer stem cell; WNT signaling; miR-600; miRNA

Year:  2017        PMID： 28868341      PMCID： PMC5540206          DOI： 10.1080/23723556.2017.1319896

Source DB:  PubMed          Journal:  Mol Cell Oncol        ISSN： 2372-3556


  9 in total

Review 1.  Concise Review: Emerging Drugs Targeting Epithelial Cancer Stem-Like Cells.

Authors:  Mehreen Ahmed; Kritika Chaudhari; Roya Babaei-Jadidi; Lodewijk V Dekker; Abdolrahman Shams Nateri
Journal:  Stem Cells       Date:  2017-03-01       Impact factor: 6.277

Review 2.  Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal.

Authors:  Myriam Hemberger; Wendy Dean; Wolf Reik
Journal:  Nat Rev Mol Cell Biol       Date:  2009-07-15       Impact factor: 94.444

3.  Design of Multimodal Small Molecules Targeting miRNAs Biogenesis: Synthesis and In Vitro Evaluation.

Authors:  Duc D Vo; Maria Duca
Journal:  Methods Mol Biol       Date:  2017

4.  miR-600 Acts as a Bimodal Switch that Regulates Breast Cancer Stem Cell Fate through WNT Signaling.

Authors:  Rita El Helou; Guillaume Pinna; Olivier Cabaud; Julien Wicinski; Ricky Bhajun; Laurent Guyon; Claire Rioualen; Pascal Finetti; Abigaelle Gros; Bernard Mari; Pascal Barbry; Francois Bertucci; Ghislain Bidaut; Annick Harel-Bellan; Daniel Birnbaum; Emmanuelle Charafe-Jauffret; Christophe Ginestier
Journal:  Cell Rep       Date:  2017-02-28       Impact factor: 9.423

Review 5.  Breast cancer stem cells programs: enter the (non)-code.

Authors:  Marion A Salvador; Daniel Birnbaum; Emmanuelle Charafe-Jauffret; Christophe Ginestier
Journal:  Brief Funct Genomics       Date:  2016-03-08       Impact factor: 4.241

Review 6.  Biological barriers to therapy with antisense and siRNA oligonucleotides.

Authors:  R Juliano; J Bauman; H Kang; X Ming
Journal:  Mol Pharm       Date:  2009 May-Jun       Impact factor: 4.939

7.  A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.

Authors:  Pengcheng Bu; Kai-Yuan Chen; Joyce Huan Chen; Lihua Wang; Jewell Walters; Yong Jun Shin; Julian P Goerger; Jian Sun; Mavee Witherspoon; Nikolai Rakhilin; Jiahe Li; Herman Yang; Jeff Milsom; Sang Lee; Warren Zipfel; Moonsoo M Jin; Zeynep H Gümüş; Steven M Lipkin; Xiling Shen
Journal:  Cell Stem Cell       Date:  2013-05-02       Impact factor: 24.633

Review 8.  Bidirectional interconversion of stem and non-stem cancer cell populations: A reassessment of theoretical models for tumor heterogeneity.

Authors:  Sanne M van Neerven; Mathijs Tieken; Louis Vermeulen; Maarten F Bijlsma
Journal:  Mol Cell Oncol       Date:  2015-12-02

9.  miR-600 inhibits cell proliferation, migration and invasion by targeting p53 in mutant p53-expressing human colorectal cancer cell lines.

Authors:  Peili Zhang; Zhigui Zuo; Aihua Wu; Wenjing Shang; Ruichun Bi; Qike Jin; Jianbo Wu; Lei Jiang
Journal:  Oncol Lett       Date:  2017-01-26       Impact factor: 2.967
  9 in total

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