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Literature DB >> 28867065

Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository.

Joy Wan¹, Jack Steiner², Eulalia Baselga³, Francine Blei⁴, Maria Cordisco⁵, Maria C Garzon⁶, Deborah S Goddard⁷, Anita Haggstrom⁸, Alfons Krol⁹, Ilona J Frieden¹⁰, Denise Metry¹¹, Kimberly D Morel⁶, Judith M A Verhagen¹², Orli Wargon¹³, Beth A Drolet¹⁴, Dawn H Siegel¹⁴.

Abstract

The cause of PHACE syndrome is unknown. In a study of 218 patients, we examined potential prenatal risk factors for PHACE syndrome. Rates of pre-eclampsia and placenta previa in affected individuals were significantly greater than in the general population. No significant risk factor differences were detected between male and female subjects.

Entities: Chemical Disease Gene Species

Keywords: disease pathogenesis; hemangioma; perinatal risk factors

Mesh：

Year: 2017 PMID： 28867065 PMCID： PMC5690843 DOI： 10.1016/j.jpeds.2017.06.055

Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406

21 in total

1. Characteristics of infantile hemangiomas as clues to pathogenesis: does hypoxia connect the dots?

Authors: Beth A Drolet; Ilona J Frieden
Journal: Arch Dermatol Date: 2010-11

2. Risk for PHACE syndrome in infants with large facial hemangiomas.

Authors: Anita N Haggstrom; Maria C Garzon; Eulalia Baselga; Sarah L Chamlin; Ilona J Frieden; Kristen Holland; Sheilagh Maguiness; Anthony J Mancini; Catherine McCuaig; Denise W Metry; Kimberly Morel; Julie Powell; Susan M Perkins; Dawn Siegel; Beth A Drolet
Journal: Pediatrics Date: 2010-07-19 Impact factor: 7.124

3. Placental hypoxia and neonatal haemangioma: clinical and histological observations.

Authors: V Colonna; L Resta; A Napoli; E Bonifazi
Journal: Br J Dermatol Date: 2009-10-26 Impact factor: 9.302

4. A prospective study of PHACE syndrome in infantile hemangiomas: demographic features, clinical findings, and complications.

Authors: D W Metry; A N Haggstrom; B A Drolet; E Baselga; S Chamlin; M Garzon; K Horii; A Lucky; A J Mancini; B Newell; A Nopper; G Heyer; I J Frieden
Journal: Am J Med Genet A Date: 2006-05-01 Impact factor: 2.802

5. Prospective study of infantile hemangiomas: demographic, prenatal, and perinatal characteristics.

Authors: Anita N Haggstrom; Beth A Drolet; Eulalia Baselga; Sarah L Chamlin; Maria C Garzon; Kimberly A Horii; Anne W Lucky; Anthony J Mancini; Denise W Metry; Brandon Newell; Amy J Nopper; Ilona J Frieden
Journal: J Pediatr Date: 2007-03 Impact factor: 4.406

6. A unique microvascular phenotype shared by juvenile hemangiomas and human placenta.

Authors: P E North; M Waner; A Mizeracki; R E Mrak; R Nicholas; J Kincannon; J Y Suen; M C Mihm
Journal: Arch Dermatol Date: 2001-05

Review 7. Pathogenesis of infantile haemangioma: new molecular and cellular insights.

Authors: Matthew R Ritter; Ross A Butschek; Martin Friedlander; Sheila F Friedlander
Journal: Expert Rev Mol Med Date: 2007-11-29 Impact factor: 5.600

8. Cardiac screening in infants with infantile hemangiomas before propranolol treatment.

Authors: Francine Blei; Doff B McElhinney; Ascanio Guarini; Salvatore Presti
Journal: Pediatr Dermatol Date: 2014-05-29 Impact factor: 1.588

9. Prospective study of infantile haemangiomas: incidence, clinical characteristics and association with placental anomalies.

Authors: A Munden; R Butschek; W L Tom; J S Marshall; D M Poeltler; S E Krohne; A B Alió; M Ritter; D F Friedlander; V Catanzarite; A Mendoza; L Smith; M Friedlander; S F Friedlander
Journal: Br J Dermatol Date: 2014-04 Impact factor: 9.302