| Literature DB >> 28866856 |
Teck-Hock Toh1,2,3, Vivian Wee-Yen Tan4, Peter Sie-Teck Lau5,6,7, Andrew Kiyu8,9.
Abstract
This study determined the accuracy of Modified Checklist for Autism in Toddlers (M-CHAT) in detecting toddlers with autism spectrum disorder (ASD) and other developmental disorders (DD) in community mother and child health clinics. We analysed 19,297 eligible toddlers (15-36 months) who had M-CHAT performed in 2006-2011. Overall sensitivities for detecting ASD and all DD were poor but better in the 21 to <27 months and 27-36-month age cohorts (54.5-64.3%). Although positive predictive value (PPV) was poor for ASD, especially the younger cohort, positive M-CHAT helped in detecting all DD (PPV = 81.6%). This suggested M-CHAT for screening ASD was accurate for older cohorts (>21 months) and a useful screening tool for all DD.Entities:
Keywords: Accuracy; Autism spectrum disorder; Community; Developmental disorders; Developmental screening; Early detection
Mesh:
Year: 2018 PMID: 28866856 DOI: 10.1007/s10803-017-3287-x
Source DB: PubMed Journal: J Autism Dev Disord ISSN: 0162-3257