Toshihiro Takami1, Kentaro Naito2, Toru Yamagata3, Shinichi Kawahara2, Kenji Ohata2. 1. Department of Neurosurgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan. Electronic address: ttakami@med.osaka-cu.ac.jp. 2. Department of Neurosurgery, Osaka City University Graduate School of Medicine, Abeno-ku, Osaka, Japan. 3. Department of Neurosurgery, Osaka City General Hospital, Miyakojima-ku, Osaka, Japan.
Abstract
BACKGROUND: Selection of the access myelotomy is a key issue in surgery for spinal intramedullary tumors. This study focused on surgical outcomes with the posterolateral sulcus (PLS) approach, equivalent to dorsal root entry zone myelotomy. METHODS: This retrospective study of the 10-year period from 2007 to 2016 included 90 cases of spinal intramedullary lesions (99 operations). A PLS approach was indicated for intramedullary lesions situated laterally in the spinal cord showing no contact with the spinal cord surface. Neurological conditions before and after surgery were carefully assessed objectively. RESULTS: A PLS approach was applied in 34 of the 99 operations (34.3%). Among 70 cases involving astrocytic tumor, ependymal tumor, cavernous malformation or hemangioblastoma, 23 cases (32.9%) were operated on using a PLS approach. Microscopically gross total or subtotal removal of the tumor was achieved in 18 of 23 cases (78.3%). These 18 cases demonstrated mild deterioration of motor function on the approach side early after surgery, but usually resolving within several months postoperatively. Average grade of the modified McCormick functional schema before surgery was maintained 6 months postoperatively. Average grade of the sensory pain scale before surgery was significantly improved by 6 months postoperatively. Segmental dysesthesia on the approach side unexpectedly remained in 2 of 18 cases (11.1%) even late after surgery. CONCLUSIONS: These findings suggest that the PLS approach can provide direct access to tumors with minimal tissue damage, when applied appropriately after careful case selection.
BACKGROUND: Selection of the access myelotomy is a key issue in surgery for spinal intramedullary tumors. This study focused on surgical outcomes with the posterolateral sulcus (PLS) approach, equivalent to dorsal root entry zone myelotomy. METHODS: This retrospective study of the 10-year period from 2007 to 2016 included 90 cases of spinal intramedullary lesions (99 operations). A PLS approach was indicated for intramedullary lesions situated laterally in the spinal cord showing no contact with the spinal cord surface. Neurological conditions before and after surgery were carefully assessed objectively. RESULTS: A PLS approach was applied in 34 of the 99 operations (34.3%). Among 70 cases involving astrocytic tumor, ependymal tumor, cavernous malformation or hemangioblastoma, 23 cases (32.9%) were operated on using a PLS approach. Microscopically gross total or subtotal removal of the tumor was achieved in 18 of 23 cases (78.3%). These 18 cases demonstrated mild deterioration of motor function on the approach side early after surgery, but usually resolving within several months postoperatively. Average grade of the modified McCormick functional schema before surgery was maintained 6 months postoperatively. Average grade of the sensory pain scale before surgery was significantly improved by 6 months postoperatively. Segmental dysesthesia on the approach side unexpectedly remained in 2 of 18 cases (11.1%) even late after surgery. CONCLUSIONS: These findings suggest that the PLS approach can provide direct access to tumors with minimal tissue damage, when applied appropriately after careful case selection.