Literature DB >> 28865

Gaucher's disease. Factors affecting the 4-methylum-belliferyl-beta-D-glucosidase activity of cultured skin fibroblasts.

J Butterworth, D M Broadhead.   

Abstract

Phosphate-buffered saline was found to inhibit acid beta-glucosidase activity of cultured cells. This effect was attributable to both the pH and the chloride content of the phosphate-buffered saline. Washing the cells in sucrose (0.25M) to remove residual phosphate-buffered saline effectively eliminated this inhibition.

Entities:  

Mesh：

Substances：

Year:  1978        PMID： 28865     DOI： 10.1111/j.1399-0004.1978.tb02109.x

Source DB:  PubMed          Journal:  Clin Genet        ISSN： 0009-9163            Impact factor:   4.438


  4 in total

1.  The inhibition of glucosylceramide beta-glucosidase and other acid hydrolases by nucleic acids.

Authors:  A Sano; N S Radin
Journal:  Biochem J       Date:  1988-08-15       Impact factor: 3.857

2.  The iduronate sulphatase activities of cells and tissue fluids from patients with Hunter syndrome and normal controls.

Authors:  M F Dean
Journal:  J Inherit Metab Dis       Date:  1983       Impact factor: 4.982

3.  Mutations of glucocerebrosidase: discrimination of neurologic and non-neurologic phenotypes of Gaucher disease.

Authors:  E I Ginns; R O Brady; S Pirruccello; C Moore; S Sorrell; F S Furbish; G J Murray; J Tager; J A Barranger
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

4.  Comparison of the substrate 4-methylumbelliferyl-alpha-l-iduronide with phenyl-alpha-L-iduronide for the diagnosis of Hurler's disease in cultured cells.

Authors:  J Butterworth; D M Broadhead
Journal:  J Inherit Metab Dis       Date:  1980       Impact factor: 4.982
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.