| Literature DB >> 2886425 |
M F Seldin, L A D'Hoostelaere, A D Steinberg, Y Saga, H C Morse.
Abstract
Allelic variants of Ly-5 in inbred commensal and other natural populations of mice were analyzed by patterns of restriction fragment length polymorphisms (RFLP) and Southern hybridization using an Ly-5 cDNA probe and by cell-surface staining with a panel of antibodies directed against polymorphic and nonpolymorphic Ly-5 determinants. New Ly-5 alleles were defined by RFLPs generated by both Eco RI and Bam HI restriction enzyme digests. The Mus musculus subspecies and other species within the genus Mus showed a strong correlation between allelic variants defined by restriction enzymes and serologic specificities. The data also suggest the conservation of the Ly-5 gene throughout the genus Mus.Entities:
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Year: 1987 PMID: 2886425 DOI: 10.1007/bf00345457
Source DB: PubMed Journal: Immunogenetics ISSN: 0093-7711 Impact factor: 2.846