Literature DB >> 2886255

Involvement of the sympathetic nervous system in lipolytic activity in brown adipose tissue of cold acclimated rats.

M C Laury, M F Chapey, R Portet.   

Abstract

In cold acclimated rats, in vitro, NE led to a significant increase in release of FFA and glycerol in denervated IBAT. In vivo, study of arteriovenous differences showed that the denervated BAT loses its full capacity to utilize FFA and glycerol released by NE. After denervation an increase of blood flow in Sulzer's vein was observed. This effect appeared immediately after intervention whereas the effect on fat metabolism appeared later. In cold acclimated rats, the sympathetic nervous system appears to be an important regulator of fatty acid metabolism in BAT.

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Year:  1987        PMID: 2886255     DOI: 10.1016/0300-9629(87)90446-4

Source DB:  PubMed          Journal:  Comp Biochem Physiol A Comp Physiol        ISSN: 0300-9629


  2 in total

1.  Prepontine knife cut-induced hyperthermia in the rat. Effect of chemical sympathectomy and surgical denervation of brown adipose tissue.

Authors:  R H Benzi; M Shibata; J Seydoux; L Girardier
Journal:  Pflugers Arch       Date:  1988-06       Impact factor: 3.657

2.  Brown adipose tissue dynamics in wild-type and UCP1-knockout mice: in vivo insights with magnetic resonance.

Authors:  Kirsten Grimpo; Maximilian N Völker; Eva N Heppe; Steve Braun; Johannes T Heverhagen; Gerhard Heldmaier
Journal:  J Lipid Res       Date:  2013-12-16       Impact factor: 5.922

  2 in total

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