Literature DB >> 28862372

Correlation of CD4 count with cariogenic oral flora indicators and dental caries in HIV-seropositive children undergoing antiretroviral therapy in Mangaluru, South India.

Soumya Muraleedharan1, Ganesh Shenoy Panchmal1, Rekha P Shenoy1, Praveen Jodalli1, Laxminarayan Sonde1, Imran Pasha1.   

Abstract

AIM: The aim of the present study was to compare the association of CD4 count with cariogenic oral flora indicators and dental caries in HIV-seropositive children receiving antiretroviral therapy (ART).
METHODS: A descriptive study was conducted among HIV-seropositive children receiving ART at Snehasadan Camillian Care and Support Center HIV/AIDS in Mangaluru, India. Demographic details and r recent CD4 counts were recorded. For dental caries, the Decayed, Missing, Filled Teeth (DMFT)/decayed, missing, filled/decayed, extracted, filled index was used. Data were analyzed using SPSS version 22. Spearman's correlation was used to correlate CD4 count with dental caries and cariogenic oral flora indicators (mutans streptococci and lactobacilli).
RESULTS: The study population comprised 35 patients. Dental caries prevalence was 54.1% in deciduous teeth and 41.2% in permanent teeth. Age and DMFT showed a significant, positive correlation; age and dmft showed a negative correlation (P < .05). A weak, negative correlation was found between age and Streptococcus mutans (S. mutans), and also CD4 count; S. mutans and CD4 count and dmft were not found to be statistically significant (P < .05).
CONCLUSION: No statistically-significant correlation was found between CD4 count and cariogenic oral flora indicators in HIV-positive patients. The presence of a minimum number of restored teeth compared to decayed teeth suggests a lack of dental care being given to HIV-positive patients.
© 2017 John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  zzm321990Lactobacilluszzm321990; zzm321990Streptococcus mutanszzm321990; HIV-seropositive; antiretroviral therapy; dental caries

Mesh:

Year:  2017        PMID: 28862372     DOI: 10.1111/jicd.12292

Source DB:  PubMed          Journal:  J Investig Clin Dent        ISSN: 2041-1618


  2 in total

1.  Dental caries status of children receiving Highly active antiretroviral therapy (HAART) - A multicentric cross-sectional study in Tamil Nadu, India.

Authors:  G Shanmugavadivel; A R Senthil Eagappan; S Dinesh; A Balatandayoudham; M Sadish; P Prasanna Kumar
Journal:  J Family Med Prim Care       Date:  2020-12-31

2.  Oral Health Status of Young People Infected with HIV in High Epidemic Area of China.

Authors:  Fei Chen; Yuewu Cheng; Tiansheng Xie
Journal:  J Multidiscip Healthc       Date:  2021-04-20
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.