Antonio Tursi1, Walter Elisei2, Marcello Picchio3, Gabriella Nasi4, Angela Maria Mastromatteo4, Francesco Di Mario5, Enrico Di Rosa6, Maria Alessandra Brandimarte6, Giovanni Brandimarte7. 1. Gastroenterology Service, ASL BAT, Andria, Italy. 2. Division of Gastroenterology, ASL RM6, Albano Laziale, Rome, Italy. 3. Division of Surgery, "P. Colombo" Hospital, ASL RM6, Velletri, Rome, Italy. 4. Clinical Management Staff, "Cristo Re" Hospital, Rome, Italy. 5. Department of Clinical & Experimental Medicine, Gastroenterology Unit, University of Parma, Parma, Italy. 6. Department of Hygiene and Public Health, ASL RM1, Rome, Italy. 7. Division of Internal Medicine and Gastroenterology, "Cristo Re" Hospital, Rome, Italy.
Abstract
BACKGROUND: Several treatments are currently advised to manage diverticular disease (DD) patients, but their impact on the burden of the disease is unknown. Our aim was to assess the economic analysis of using the recent Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification on the burden of medical therapies prescribed in preventing DD complications occurrence in Italy. METHODS: We assessed retrospectively the cost/year of treatments in estimated DICA 1, DICA 2 and DICA 3 population. Analysis of diverticulosis prevalence was estimated according to data population provided by Italian Institute of Statistics (ISTAT). Cost of treatments calculated according to data on drugs' consumption collected during the DICA study. RESULTS: We estimated that >8 million of Italian people >60 years may have diverticulosis, and that about 75% of diverticular population are on DICA 1, about 30% on DICA 2, and about 13% on DICA 3. We estimated that >387 million of euros could be spent in DICA 1 population, >203 million of euros in DICA 2 population, and >88 million of euros in DICA 3 population. Since medical treatments did not show any significant advantage when treating DICA 1 and DICA 3 people in terms of prevention of acute diverticulitis occurrence/recurrence and surgery occurrence, we can estimated that >475 million of euros could be spent in Italy without any significant benefit in preventing DD complications occurrence. CONCLUSIONS: DICA endoscopic classification may have a significant impact on the burden of DD in Italy, because it helps to select DD people who effectively need treatments in terms of prevention of acute diverticulitis occurrence/recurrence and surgery occurrence.
BACKGROUND: Several treatments are currently advised to manage diverticular disease (DD) patients, but their impact on the burden of the disease is unknown. Our aim was to assess the economic analysis of using the recent Diverticular Inflammation and Complication Assessment (DICA) endoscopic classification on the burden of medical therapies prescribed in preventing DD complications occurrence in Italy. METHODS: We assessed retrospectively the cost/year of treatments in estimated DICA 1, DICA 2 and DICA 3 population. Analysis of diverticulosis prevalence was estimated according to data population provided by Italian Institute of Statistics (ISTAT). Cost of treatments calculated according to data on drugs' consumption collected during the DICA study. RESULTS: We estimated that >8 million of Italian people >60 years may have diverticulosis, and that about 75% of diverticular population are on DICA 1, about 30% on DICA 2, and about 13% on DICA 3. We estimated that >387 million of euros could be spent in DICA 1 population, >203 million of euros in DICA 2 population, and >88 million of euros in DICA 3 population. Since medical treatments did not show any significant advantage when treating DICA 1 and DICA 3 people in terms of prevention of acute diverticulitis occurrence/recurrence and surgery occurrence, we can estimated that >475 million of euros could be spent in Italy without any significant benefit in preventing DD complications occurrence. CONCLUSIONS: DICA endoscopic classification may have a significant impact on the burden of DD in Italy, because it helps to select DDpeople who effectively need treatments in terms of prevention of acute diverticulitis occurrence/recurrence and surgery occurrence.
Entities:
Keywords:
Acute diverticulitis; Diverticular Inflammation and Complication Assessment classification (DICA classification); burden; prevention; surgery
Authors: A Tursi; W Elisei; M Picchio; G Forti; G Giorgetti; R Faggiani; C Zampaletta; G Brandimarte Journal: Aliment Pharmacol Ther Date: 2014-04 Impact factor: 8.171
Authors: Antonio Tursi; Giovanni Brandimarte; Francesco Di Mario; Maria L Annunziata; Mauro Bafutto; Maria A Bianco; Raffaele Colucci; Rita Conigliaro; Silvio Danese; Rudi De Bastiani; Walter Elisei; Ricardo Escalante; Roberto Faggiani; Luciano Ferrini; Giacomo Forti; Giovanni Latella; Maria G Graziani; Enio C Oliveira; Alfredo Papa; Antonio Penna; Piero Portincasa; Kjetil Søreide; Antonio Spadaccini; Paolo Usai; Stefanos Bonovas; Carmelo Scarpignato; Marcello Picchio; Piera G Lecca; Costantino Zampaletta; Claudio Cassieri; Alberto Damiani; Kari F Desserud; Serafina Fiorella; Rosario Landi; Elisabetta Goni; Maria A Lai; Flavia Pigò; Gianluca Rotondano; Giuseppe Schiaccianoce Journal: United European Gastroenterol J Date: 2015-11-13 Impact factor: 4.623
Authors: Antonio Tursi; Marcello Picchio; Walter Elisei; Francesco Di Mario; Carmelo Scarpignato; Giovanni Brandimarte Journal: J Clin Gastroenterol Date: 2016-10 Impact factor: 3.062