Literature DB >> 28861307

Preliminary feasibility study of a new method of hypothermia in an experimental canine model.

İbrahim Ünal Sert1, Murat Akand2, Özcan Kılıç2, Nuri Yavru3, Ersan Bulut4.   

Abstract

OBJECTIVE: To build up a new microcontroller thermoelectric system to achieve renal hypothermia.
MATERIAL AND METHODS: Renal hypothermia system was tested under in vivo conditions in the kidneys of ten Mongrel dogs. Ambient temperature was evaluated using two different microcontrollers. In order to ensure hypothermia in the renal parenchyma, selection can be made among 4 modules and sensors which detect the temperature of the area. The temperature range of the system was adjusted between -50°C and +50°C.
RESULTS: When single and double poles of the kidney were cooled, initial mean intraperitoneal temperature values were found 37.7°C for rectum and 36.5°C for renal cortex and medulla. After the temperature of the cooling module was set to 12°C, the module was placed on the poles of the kidney. After fifteen minutes, temperature was 15.4°C in the lower pole of the kidney, 28.1°C in the cortex of the other side and 29.2°C in the intramedullary region. The temperature was found to be 15°C in the vicinity and 26.1°C in the cortex across the module. After the system was stabilized, a very slight change was observed in the temperature.
CONCLUSION: Hypothermia system developed ensured desired cooling of the targeted part of the kidney; however, it did not cause a change in the temperature of other parts of the kidney or general body temperature. Thus, it was possible to create a long-term study area for renal parenchymal surgery.

Entities:  

Keywords:  Hypothermia; partial nephrectomy; renal surgery; thermo-electric system

Year:  2017        PMID: 28861307      PMCID: PMC5562254          DOI: 10.5152/tud.2017.26878

Source DB:  PubMed          Journal:  Turk J Urol        ISSN: 2149-3235


  18 in total

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4.  Intrarenal and in situ kidney workbench surgery under hypothermia.

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Journal:  Urology       Date:  1980-02       Impact factor: 2.649

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7.  Renal hypothermia achieved by retrograde endoscopic cold saline perfusion: technique and initial clinical application.

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Journal:  Urology       Date:  2003-05       Impact factor: 2.649

8.  Regional hypothermia of the kidney: surface or transarterial perfusion cooling? A functional study.

Authors:  M Marberger; F Eisenberger
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9.  Ischemic renal damage after nephron-sparing surgery in patients with normal contralateral kidney.

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10.  An evaluation of techniques used for the production of temporary renal ischaemia.

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Journal:  Br J Urol       Date:  1978-10
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