Literature DB >> 28860406

Vascularised fibular grafts for reconstruction of extremity bone defects after resection of bone and soft-tissue tumours : a single institutional study of 49 patients.

M Emori1, M Kaya2, H Irifune1, N Takahashi1, J Shimizu1, E Mizushima1, Y Murahashi1, T Yamashita1.   

Abstract

AIMS: The aims of this study were to analyse the long-term outcome of vascularised fibular graft (VFG) reconstruction after tumour resection and to evaluate the usefulness of the method. PATIENTS AND METHODS: We retrospectively reviewed 49 patients who had undergone resection of a sarcoma and reconstruction using a VFG between 1988 and 2015. Their mean follow-up was 98 months (5 to 317). Reconstruction was with an osteochondral graft (n = 13), intercalary graft (n = 12), inlay graft (n = 4), or resection arthrodesis (n = 20). We analysed the oncological and functional outcome, and the rate of bony union and complications.
RESULTS: Five- and ten-year overall survival rates were 89% and 86%, respectively. Local recurrence occurred in two patients. Eight patients developed pulmonary metastases. Bone union was achieved in 44 patients (90%). Fracture occurred in six patients (12%), infection in three (6%), and nonunion in five (10%). The mean Musculoskeletal Tumor Society (MSTS) scores were as follows: osteochondral graft 70%; intercalary graft 73%; inlay graft 89%; and resection arthrodesis 83%.
CONCLUSION: Although associated with a relatively high rate of complications, each reconstruction method is useful, with a high rate of successful limb salvage and a good long-term functional outcome. Cite this article: Bone Joint J 2017;99-B:1237-43. ©2017 The British Editorial Society of Bone & Joint Surgery.

Entities:  

Keywords:  Bone and soft-tissue tumour; Vascularised fibula graft

Mesh:

Year:  2017        PMID: 28860406     DOI: 10.1302/0301-620X.99B9.BJJ-2017-0219.R1

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  7 in total

Review 1.  How the Choice of Osteosynthesis Affects the Complication Rate of Intercalary Allograft Reconstruction? A Systematic Review and Meta-analysis.

Authors:  Khodamorad Jamshidi; Mansour Bahardoust; Arman Karimi Behnagh; Abolfazl Bagherifard; Alireza Mirzaei
Journal:  Indian J Orthop       Date:  2021-11-10       Impact factor: 1.251

2.  Intercalary allograft reconstruction following femoral tumour resection: mid- and long-term results and benefits of adding a vascularised fibula autograft.

Authors:  Vincent Crenn; Yonis Quinette; Charlie Bouthors; Gilles Missenard; Brice Viard; Philippe Anract; Stéphane Boisgard; Eric Mascard; François Gouin
Journal:  World J Surg Oncol       Date:  2022-06-13       Impact factor: 3.253

3.  Mettl3 Regulates Osteogenic Differentiation and Alternative Splicing of Vegfa in Bone Marrow Mesenchymal Stem Cells.

Authors:  Cheng Tian; Yanlan Huang; Qimeng Li; Zhihui Feng; Qiong Xu
Journal:  Int J Mol Sci       Date:  2019-01-28       Impact factor: 5.923

4.  Clinical Outcome of Free Vascularized Fibula Graft in the Surgical Treatment of Extremity Osteosarcoma.

Authors:  Leilei Xu; Li Wen; Jun Qiao; Zezhang Zhu; Yong Qiu; Jin Xiong; Haijun Mao; Shoufeng Wang
Journal:  Orthop Surg       Date:  2020-05-15       Impact factor: 2.071

Review 5.  Complication of osteo reconstruction by utilizing free vascularized fibular bone graft.

Authors:  Qifeng Ou; Panfeng Wu; Zhengbing Zhou; Ding Pan; Ju-Yu Tang
Journal:  BMC Surg       Date:  2020-10-02       Impact factor: 2.102

6.  Osteofibrous dysplasia-like adamantinoma treated via intercalary segmental resection with partial cortex preservation using pedicled vascularized fibula graft: a case report.

Authors:  Yuji Yamamura; Makoto Emori; Nobuyuki Takahashi; Mitsumasa Chiba; Junya Shimizu; Yasutaka Murahashi; Shintaro Sugita; Kousuke Iba; Tadashi Hasegawa; Toshihiko Yamashita
Journal:  World J Surg Oncol       Date:  2020-08-13       Impact factor: 2.754

Review 7.  Strategies for large bone defect reconstruction after trauma, infections or tumour excision: a comprehensive review of the literature.

Authors:  Filippo Migliorini; Gerardo La Padula; Ernesto Torsiello; Filippo Spiezia; Francesco Oliva; Nicola Maffulli
Journal:  Eur J Med Res       Date:  2021-10-02       Impact factor: 2.175

  7 in total

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