Literature DB >> 28859896

HIV-1 mutates to adapt in fluxing environments.

Masako Nomaguchi1, Naoya Doi1, Takaaki Koma1, Akio Adachi2.   

Abstract

Human immunodeficiency virus type 1 (HIV-1) is specifically adapted for replication, persistence, transmission, and survival in humans. HIV-1 is highly mutable in nature, and well responds to a variety of environmental pressures by altering its genome sequences. In this review, we have described experimental evidence that demonstrates this phantasmagoric property of HIV-1.
Copyright © 2017 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

Entities:  

Keywords:  Adaptive mutations; Escape mutations; HIV-1; Sequence variations

Mesh：

Year:  2017        PMID： 28859896     DOI： 10.1016/j.micinf.2017.08.003

Source DB:  PubMed          Journal:  Microbes Infect        ISSN： 1286-4579            Impact factor:   2.700


  2 in total

1.  Microbes and Infection turns 20.

Authors:  Sophia J Häfner; David M Ojcius
Journal:  Microbes Infect       Date:  2018-05-30       Impact factor: 2.700

2.  HIV chromatin is a preferred target for drugs that bind in the DNA minor groove.

Authors:  Clayton K Collings; Donald W Little; Samuel J Schafer; John N Anderson
Journal:  PLoS One       Date:  2019-12-30       Impact factor: 3.240
  2 in total

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