Literature DB >> 28857991

Spontaneous Healing of Clodronate-Related Osteonecrosis of the Jaw.

Enrico Nastro Siniscalchi1, Alessandro Allegra, Francesco Saverio De Ponte, Giacomo Oteri, Gabriele Cervino, Floriana Lauritano, Caterina Musolino, Marco Cicciù.   

Abstract

Cases of medication-related osteonecrosis of the jaw (MRONJ) have been more commonly associated with aminobiphosphonate therapy than with alkylbiphosphonate treatment. Here, we report a case of MRONJ in a subject who received an alkylbiphosphonate, clodronate, for the treatment of osteoporosis, and discuss the pathogenic mechanisms of alkylbiphosphonates and the possible reasons for the spontaneous and rapid remission of MRONJ occurring in our patient.

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Year:  2017        PMID: 28857991     DOI: 10.1097/SCS.0000000000003837

Source DB:  PubMed          Journal:  J Craniofac Surg        ISSN: 1049-2275            Impact factor:   1.046


  1 in total

1.  Effectiveness of thiazides on serum and urinary calcium levels and bone mineral density in patients with osteoporosis: a systematic review and meta-analysis.

Authors:  Lei Cheng; Keyan Zhang; Zhenyong Zhang
Journal:  Drug Des Devel Ther       Date:  2018-11-14       Impact factor: 4.162

  1 in total

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