Literature DB >> 28856606

1H, 15N and 13C sequence specific backbone assignment of the vanadate inhibited hematopoietic tyrosine phosphatase.

Luciana E S F Machado1,2, Rebecca Page3,2, Wolfgang Peti4,5.   

Abstract

The sequence-specific backbone assignment of hematopoietic protein tyrosine phosphatase (HePTP; PTPN7) in presence of vanadate has been determined, based on triple-resonance experiments using uniformly [13C,15N]-labeled protein. These assignments facilitate further studies of HePTP in the presence of inhibitors to target leukemia and provide further insights into the function of protein tyrosine phosphatases.

Entities:  

Keywords:  HePTP; Inhibition; Leukemia; Protein dynamics; Protein tyrosine phosphatase; Vanadate

Mesh：

Substances：

Year:  2017        PMID： 28856606      PMCID： PMC5832517          DOI： 10.1007/s12104-017-9770-7

Source DB:  PubMed          Journal:  Biomol NMR Assign        ISSN： 1874-270X            Impact factor:   0.746


  10 in total

1.  Differential interaction of the tyrosine phosphatases PTP-SL, STEP and HePTP with the mitogen-activated protein kinases ERK1/2 and p38alpha is determined by a kinase specificity sequence and influenced by reducing agents.

Authors:  Juan José Muñoz; Céline Tárrega; Carmen Blanco-Aparicio; Rafael Pulido
Journal:  Biochem J       Date:  2003-05-15       Impact factor: 3.857

2.  Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation.

Authors:  Eduard Sergienko; Jian Xu; Wallace H Liu; Russell Dahl; David A Critton; Ying Su; Brock T Brown; Xochella Chan; Li Yang; Ekaterina V Bobkova; Stefan Vasile; Hongbin Yuan; Justin Rascon; Sharon Colayco; Shyama Sidique; Nicholas D P Cosford; Thomas D Y Chung; Tomas Mustelin; Rebecca Page; Paul J Lombroso; Lutz Tautz
Journal:  ACS Chem Biol       Date:  2011-11-17       Impact factor: 5.100

3.  Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase).

Authors:  B Zanke; H Suzuki; K Kishihara; L Mizzen; M Minden; A Pawson; T W Mak
Journal:  Eur J Immunol       Date:  1992-01       Impact factor: 5.532

Review 4.  Strategies to maximize heterologous protein expression in Escherichia coli with minimal cost.

Authors:  Wolfgang Peti; Rebecca Page
Journal:  Protein Expr Purif       Date:  2006-07-04       Impact factor: 1.650

5.  Conformational Rigidity and Protein Dynamics at Distinct Timescales Regulate PTP1B Activity and Allostery.

Authors:  Meng S Choy; Yang Li; Luciana E S F Machado; Micha B A Kunze; Christopher R Connors; Xingyu Wei; Kresten Lindorff-Larsen; Rebecca Page; Wolfgang Peti
Journal:  Mol Cell       Date:  2017-02-16       Impact factor: 17.970

6.  Structural basis of p38α regulation by hematopoietic tyrosine phosphatase.

Authors:  Dana M Francis; Bartosz Różycki; Dorothy Koveal; Gerhard Hummer; Rebecca Page; Wolfgang Peti
Journal:  Nat Chem Biol       Date:  2011-11-06       Impact factor: 15.040

7.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

8.  A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome 1q32.1.

Authors:  B Zanke; J Squire; H Griesser; M Henry; H Suzuki; B Patterson; M Minden; T W Mak
Journal:  Leukemia       Date:  1994-02       Impact factor: 11.528

9.  Sequence-specific 1H, 13C and 15N backbone resonance assignments of the 34 kDa catalytic domain of human PTPN7.

Authors:  Mark Jeeves; Darren M McClelland; Alastair J Barr; Michael Overduin
Journal:  Biomol NMR Assign       Date:  2008-05-30       Impact factor: 0.746

10.  The CCPN data model for NMR spectroscopy: development of a software pipeline.

Authors:  Wim F Vranken; Wayne Boucher; Tim J Stevens; Rasmus H Fogh; Anne Pajon; Miguel Llinas; Eldon L Ulrich; John L Markley; John Ionides; Ernest D Laue
Journal:  Proteins       Date:  2005-06-01
  10 in total

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