Gianluca Pontone1,2, Patrizia Carità3, Mark G Rabbat4,5, Marco Guglielmo6, Andrea Baggiano6, Giuseppe Muscogiuri6,7, Andrea I Guaricci8,9. 1. Centro Cardiologico Monzino, IRCCS, Via C. Parea 4, 20138, Milan, Italy. gianluca.pontone@ccfm.it. 2. Yonsei University Health System, Seoul, South Korea. gianluca.pontone@ccfm.it. 3. Department of Cardiology, San Giovanni Di Dio Hospital, Agrigento, Italy. 4. Department of Medicine and Radiology, Division of Cardiology, Loyola University Chicago, Chicago, IL, USA. 5. Edward Hines Jr. Veteran's Affairs Hospital, Hines, IL, USA. 6. Centro Cardiologico Monzino, IRCCS, Via C. Parea 4, 20138, Milan, Italy. 7. CMO, Torre Annunziata (Napoli), Italy. 8. Institute of Cardiovascular Disease, Department of Emergency and Organ Transplantation, University Hospital 'Policlinico Consorziale' of Bari, Bari, Italy. 9. Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Abstract
PURPOSE OF REVIEW: The purpose of the present paper is to analytically review the diagnostic and prognostic role of CMR in ST-segment elevation myocardial infarction (STEMI) survivors. Percutaneous coronary intervention (PCI) is the treatment of choice in patients STEMI. However, risk of future events remains substantial. Assessment of the extent of myocardial infarction (MI), cardiac function and ventricular remodelling has become the focus of recent studies. Electrocardiography, angiography and echocardiography parameters, as well as risk scores, lack sensitivity and reproducibility in predicting future cardiovascular events. A major advantage of cardiac magnetic resonance imaging (CMR) is that it provides myocardial tissue characterization. RECENT FINDINGS: CMR is able to quantify both reversible and irreversible myocardial injury and correlates with future events. This review will illustrate how microvascular function indices (myocardial salvage index, presence and amount of microvascular obstruction and intramyocardial haemorrhage) detectable by CMR add prognostic information and could impact on future strategies to improve outcomes in revascularized patients.
PURPOSE OF REVIEW: The purpose of the present paper is to analytically review the diagnostic and prognostic role of CMR in ST-segment elevation myocardial infarction (STEMI) survivors. Percutaneous coronary intervention (PCI) is the treatment of choice in patients STEMI. However, risk of future events remains substantial. Assessment of the extent of myocardial infarction (MI), cardiac function and ventricular remodelling has become the focus of recent studies. Electrocardiography, angiography and echocardiography parameters, as well as risk scores, lack sensitivity and reproducibility in predicting future cardiovascular events. A major advantage of cardiac magnetic resonance imaging (CMR) is that it provides myocardial tissue characterization. RECENT FINDINGS: CMR is able to quantify both reversible and irreversible myocardial injury and correlates with future events. This review will illustrate how microvascular function indices (myocardial salvage index, presence and amount of microvascular obstruction and intramyocardial haemorrhage) detectable by CMR add prognostic information and could impact on future strategies to improve outcomes in revascularized patients.
Entities:
Keywords:
Cardiac magnetic resonance; Diagnosis; Prognosis; STEMI; Tissue characterization
Authors: Anna S Petronio; Marco De Carlo; Nicola Ciabatti; Giovanni Amoroso; Ugo Limbruno; Caterina Palagi; Vitantonio Di Bello; Maria F Romano; Mario Mariani Journal: Am Heart J Date: 2005-11 Impact factor: 4.749
Authors: Gregg W Stone; Harry P Selker; Holger Thiele; Manesh R Patel; James E Udelson; E Magnus Ohman; Akiko Maehara; Ingo Eitel; Christopher B Granger; Paul L Jenkins; Melissa Nichols; Ori Ben-Yehuda Journal: J Am Coll Cardiol Date: 2016-04-12 Impact factor: 24.094
Authors: Javier Ganame; Giancarlo Messalli; Steven Dymarkowski; Frank E Rademakers; Walter Desmet; Frans Van de Werf; Jan Bogaert Journal: Eur Heart J Date: 2009-04-03 Impact factor: 29.983
Authors: Heerajnarain Bulluck; Stefania Rosmini; Amna Abdel-Gadir; Anish N Bhuva; Thomas A Treibel; Marianna Fontana; Esther Gonzalez-Lopez; Manish Ramlall; Ashraf Hamarneh; Alex Sirker; Anna S Herrey; Charlotte Manisty; Derek M Yellon; James C Moon; Derek J Hausenloy Journal: J Magn Reson Imaging Date: 2017-02-15 Impact factor: 4.813
Authors: Francesca Baessato; Marco Guglielmo; Giuseppe Muscogiuri; Andrea Baggiano; Laura Fusini; Stefano Scafuri; Mario Babbaro; Rocco Mollace; Ada Collevecchio; Andrea I Guaricci; Gianluca Pontone Journal: Biomed Res Int Date: 2021-01-14 Impact factor: 3.411
Authors: Divan Gabriel Topal; Kiril Aleksov Ahtarovski; Jacob Lønborg; Dan Høfsten; Lars Nepper-Christensen; Kasper Kyhl; Mikkel Schoos; Adam Ali Ghotbi; Christoffer Göransson; Litten Bertelsen; Lene Holmvang; Steffen Helqvist; Frants Pedersen; Renate Schnabel; Lars Køber; Henning Kelbæk; Niels Vejlstrup; Thomas Engstrøm; Peter Clemmensen Journal: Int J Cardiol Heart Vasc Date: 2021-03-02