A N Ocheke1, I E Ocheke2, P A Agaba3, G E Imadde1, O A Silas4, O I Ajetunmobi4, Eche John Godwins4, C Ekere1, A Sendeht1, J Bitrus1, E I Agaba5, A S Sagay1. 1. Department of Obstetrics and Gynaecology,Faculty of Medical Sciences, University of Jos, Jos, Nigeria. 2. Department of Paediatrics,Faculty of Medical Sciences, University of Jos, Jos, Nigeria. 3. Department of Family medicine, Faculty of Medical Sciences, University of Jos, Jos, Nigeria. 4. Department of Histopathology, Faculty of Medical Sciences, University of Jos, Jos, Nigeria. 5. Department of Medicine, Faculty of Medical Sciences, University of Jos, Jos, Nigeria.
Abstract
BACKGROUND: Clinical Chorioamnionitis contributes to maternal and neonatal morbidity and mortality but the effect of histological chorioamnionitis is sparse in our environment. AIM: To determine the maternal and neonatal outcomes of histological chorioamnionitis amongst pregnant women and their babies. DESIGN OF THE STUDY: Cross sectional longitudinal study. SETTING: Jos University Teaching Hospital (JUTH), Jos, Nigeria. METHODOLOGY: Parturients were interviewed and examined as well as had their placenta examined histologically for chorioamnionitis. They and their babies were followed up for 6 weeks after delivery to monitor for any complications that may arise. RESULTS: A total of 148 parturients were enrolled from the labour ward of Jos University Teaching Hospital and of these 90 (60.8%) had histologic chorioamnionitis (HCA). As regards outcome, 9(10%) with histologic chorioamnionitis as well as 5(8.62%) of those without HCA had premature delivery. Low birth weight occurred in 12(13.33%) and 6(10.34 %) of those with HCA and without HCA respectively. In all, 1(1.47%) and 1(2.56%) of women with HCA and without HCA correspondingly had neonatal sepsis. Puerperal sepsis occurred in 2(2.94%) of those with HCA and 2(5.13%) of those without HCA. CONCLUSION: Our study has demonstrated that histological chorioamnionitis had no adverse maternal or neonatal effect. There is the need for more studies investigating the cause and the implication of histological chorioamnionitis.
BACKGROUND: Clinical Chorioamnionitis contributes to maternal and neonatal morbidity and mortality but the effect of histological chorioamnionitis is sparse in our environment. AIM: To determine the maternal and neonatal outcomes of histological chorioamnionitis amongst pregnant women and their babies. DESIGN OF THE STUDY: Cross sectional longitudinal study. SETTING: Jos University Teaching Hospital (JUTH), Jos, Nigeria. METHODOLOGY: Parturients were interviewed and examined as well as had their placenta examined histologically for chorioamnionitis. They and their babies were followed up for 6 weeks after delivery to monitor for any complications that may arise. RESULTS: A total of 148 parturients were enrolled from the labour ward of Jos University Teaching Hospital and of these 90 (60.8%) had histologic chorioamnionitis (HCA). As regards outcome, 9(10%) with histologic chorioamnionitis as well as 5(8.62%) of those without HCA had premature delivery. Low birth weight occurred in 12(13.33%) and 6(10.34 %) of those with HCA and without HCA respectively. In all, 1(1.47%) and 1(2.56%) of women with HCA and without HCA correspondingly had neonatal sepsis. Puerperal sepsis occurred in 2(2.94%) of those with HCA and 2(5.13%) of those without HCA. CONCLUSION: Our study has demonstrated that histological chorioamnionitis had no adverse maternal or neonatal effect. There is the need for more studies investigating the cause and the implication of histological chorioamnionitis.
Authors: Carl A Nath; Cande V Ananth; John C Smulian; Susan Shen-Schwarz; Lillian Kaminsky Journal: Am J Obstet Gynecol Date: 2007-09 Impact factor: 8.661
Authors: Celeste Beck; Kelly Gallagher; Leigh A Taylor; Jeffery A Goldstein; Leena B Mithal; Alison D Gernand Journal: Obstet Gynecol Date: 2021-06-01 Impact factor: 7.623