| Literature DB >> 28855730 |
Suzanne N Shapira1, Patrick Seale1.
Abstract
Brown adipose tissue is a key metabolic organ that oxidizes fatty acids and glucose to generate heat. Through epigenomic analyses of multiple adipose depots, the transcription factor nuclear factor I-A (NFIA) is now shown to drive the brown fat genetic program through binding to lineage-specific cis-regulatory elements.Entities:
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Year: 2017 PMID: 28855730 PMCID: PMC5761334 DOI: 10.1038/ncb3591
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824