Literature DB >> 28855729

A fruitful liaison of ZSCAN10 and ROS on the road to rejuvenation.

Clea Bárcena1, Carlos López-Otín1.   

Abstract

Induced pluripotent stem cells derived from aged donors (A-iPSCs) usually show genomic instability that affects their utility and raises concerns about their safety. Now, a study highlights the importance of ZSCAN10-dependent recovery of glutathione-ROS homeostasis in counteracting the genomic defects in A-iPSCs.

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Year:  2017        PMID： 28855729     DOI： 10.1038/ncb3602

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  14 in total

Review 1.  Metabolic regulation of hematopoietic stem cells in the hypoxic niche.

Authors:  Toshio Suda; Keiyo Takubo; Gregg L Semenza
Journal:  Cell Stem Cell       Date:  2011-10-04       Impact factor: 24.633

2.  NF-κB activation impairs somatic cell reprogramming in ageing.

Authors:  Clara Soria-Valles; Fernando G Osorio; Ana Gutiérrez-Fernández; Alejandro De Los Angeles; Clara Bueno; Pablo Menéndez; José I Martín-Subero; George Q Daley; José M P Freije; Carlos López-Otín
Journal:  Nat Cell Biol       Date:  2015-07-27       Impact factor: 28.824

3.  Zfp206, Oct4, and Sox2 are integrated components of a transcriptional regulatory network in embryonic stem cells.

Authors:  Hong-bing Yu; Galih Kunarso; Felicia Huimei Hong; Lawrence W Stanton
Journal:  J Biol Chem       Date:  2009-09-09       Impact factor: 5.157

Review 4.  Apoptosis and glutathione: beyond an antioxidant.

Authors:  R Franco; J A Cidlowski
Journal:  Cell Death Differ       Date:  2009-08-07       Impact factor: 15.828

5.  ATM activation by oxidative stress.

Authors:  Zhi Guo; Sergei Kozlov; Martin F Lavin; Maria D Person; Tanya T Paull
Journal:  Science       Date:  2010-10-22       Impact factor: 47.728

6.  Influence of donor age on induced pluripotent stem cells.

Authors:  Valentina Lo Sardo; William Ferguson; Galina A Erikson; Eric J Topol; Kristin K Baldwin; Ali Torkamani
Journal:  Nat Biotechnol       Date:  2016-12-12       Impact factor: 54.908

7.  Optimal ROS Signaling Is Critical for Nuclear Reprogramming.

Authors:  Gang Zhou; Shu Meng; Yanhui Li; Yohannes T Ghebre; John P Cooke
Journal:  Cell Rep       Date:  2016-04-21       Impact factor: 9.423

8.  Zfp206 regulates ES cell gene expression and differentiation.

Authors:  Wen Zhang; Emily Walker; Owen J Tamplin; Janet Rossant; William L Stanford; Timothy R Hughes
Journal:  Nucleic Acids Res       Date:  2006-09-13       Impact factor: 16.971

9.  Common genetic variation drives molecular heterogeneity in human iPSCs.

Authors:  Helena Kilpinen; Angela Goncalves; Andreas Leha; Vackar Afzal; Kaur Alasoo; Sofie Ashford; Sendu Bala; Dalila Bensaddek; Francesco Paolo Casale; Oliver J Culley; Petr Danecek; Adam Faulconbridge; Peter W Harrison; Annie Kathuria; Davis McCarthy; Shane A McCarthy; Ruta Meleckyte; Yasin Memari; Nathalie Moens; Filipa Soares; Alice Mann; Ian Streeter; Chukwuma A Agu; Alex Alderton; Rachel Nelson; Sarah Harper; Minal Patel; Alistair White; Sharad R Patel; Laura Clarke; Reena Halai; Christopher M Kirton; Anja Kolb-Kokocinski; Philip Beales; Ewan Birney; Davide Danovi; Angus I Lamond; Willem H Ouwehand; Ludovic Vallier; Fiona M Watt; Richard Durbin; Oliver Stegle; Daniel J Gaffney
Journal:  Nature       Date:  2017-05-10       Impact factor: 49.962

10.  Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death.

Authors:  Emarndeena H Cheteh; Martin Augsten; Helene Rundqvist; Julie Bianchi; Victoria Sarne; Lars Egevad; Vladimir Jn Bykov; Arne Östman; Klas G Wiman
Journal:  Cell Death Dis       Date:  2017-06-01       Impact factor: 8.469
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  1 in total

1.  ZSCAN10 promotes cell proliferation, upregulates OCT4 expression, and activates Wnt/β-catenin signaling in glioma.

Authors:  Yuan Jiang; Hongming Huang; Xingen Zhu; Miaojing Wu; Minhua Ye; Bing Xiao; Cong Yu; Hua Fang; Feng Liu; Shigang Lv
Journal:  Int J Clin Exp Pathol       Date:  2019-03-01
  1 in total

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