Literature DB >> 28854799

Photodynamic Effect of some Phthalocyanines on Enveloped and Naked Viruses.

L Nikolaeva-Glomb, L Mukova, N Nikolova, V Kussovski, L Doumanova, V Mantareva, I Angelov, D Wöhrle, A S Galabov.   

Abstract

Activity of three photosensitizing phthalocyanine derivatives was tested for photodynamic inactivation towards two coated and two non-enveloped viruses - bovine viral diarrhea virus (BVDV), influenza virus A(H3N2), poliovirus type 1 (PV-1) and human adenovirus type 5 (HAdV5). In the case of coated viruses, a combination of virucidal and irradiation effects was registered by octa-methylpyridyloxy-substituted Ga phthalocyanine (Ga8) toward BVDV, whereas tetra-methylpyridyloxy-substituted Ga phthalocyanine (Ga4) revealed a marked photoinactivation only. No such effect was observed towards influenza A virus. In contrast, the photoinactivating potential of Ga4 and Ga8 marked very high values on naked viruses, especially on HAdV5, at which both the virucidal as well as the irradiation effects became combined.

Entities:  

Keywords:  phthalocyanine; photodynamic inactivation; virus.

Mesh：

Substances：

Year:  2017        PMID： 28854799     DOI： 10.4149/av_2017_313

Source DB:  PubMed          Journal:  Acta Virol        ISSN： 0001-723X            Impact factor:   1.162


  6 in total

1.  Interactions of Co, Cu, and non-metal phthalocyanines with external structures of SARS-CoV-2 using docking and molecular dynamics.

Authors:  Wilson Luna Machado Alencar; Tiago da Silva Arouche; Abel Ferreira Gomes Neto; Teodorico de Castro Ramalho; Raul Nunes de Carvalho Júnior; Antonio Maia de Jesus Chaves Neto
Journal:  Sci Rep       Date:  2022-02-28       Impact factor: 4.379

2.  Photodynamic Inactivation of Antibiotic-Resistant and Sensitive Aeromonas hydrophila with Peripheral Pd(II)- vs. Zn(II)-Phthalocyanines.

Authors:  Vanya N Mantareva; Vesselin Kussovski; Petya Orozova; Lyudmila Dimitrova; Irem Kulu; Ivan Angelov; Mahmut Durmus; Hristo Najdenski
Journal:  Biomedicines       Date:  2022-02-05

3.  Potential Drugs Targeting Early Innate Immune Evasion of SARS-Coronavirus 2 via 2'-O-Methylation of Viral RNA.

Authors:  José Antonio Encinar; Javier A Menendez
Journal:  Viruses       Date:  2020-05-10       Impact factor: 5.048

Review 4.  The Application of Porphyrins and Their Analogues for Inactivation of Viruses.

Authors:  Natalya Sh Lebedeva; Yury A Gubarev; Mikhail O Koifman; Oskar I Koifman
Journal:  Molecules       Date:  2020-09-23       Impact factor: 4.411

5.  A Comparison of Porphyrin Photosensitizers in Photodynamic Inactivation of RNA and DNA Bacteriophages.

Authors:  Joe Heffron; Matthew Bork; Brooke K Mayer; Troy Skwor
Journal:  Viruses       Date:  2021-03-23       Impact factor: 5.048

6.  Antiviral photodynamic therapy: Inactivation and inhibition of SARS-CoV-2 in vitro using methylene blue and Radachlorin.

Authors:  Victor A Svyatchenko; Sergey D Nikonov; Alexander P Mayorov; Mark L Gelfond; Valery B Loktev
Journal:  Photodiagnosis Photodyn Ther       Date:  2020-11-26       Impact factor: 3.577
  6 in total

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