Literature DB >> 2885400

Taxol and derivatives: a biogenetic hypothesis.

F Guéritte-Voegelein, D Guénard, P Potier.   

Abstract

Based on the structural differences of compounds isolated from various species of Taxus, this brief review suggests a biogenetic approach to taxol. This hypothesis could be of some help in the synthesis of this complex molecule exhibiting significant antitumor properties.

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Year:  1987        PMID： 2885400     DOI： 10.1021/np50049a002

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli.

Authors:  K Walker; R Croteau
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-18       Impact factor: 11.205

2.  Random sequencing of an induced Taxus cell cDNA library for identification of clones involved in Taxol biosynthesis.

Authors:  Stefan Jennewein; Mark R Wildung; MyDoanh Chau; Kevin Walker; Rodney Croteau
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-03       Impact factor: 11.205

3.  Taxol biosynthesis and molecular genetics.

Authors:  Rodney Croteau; Raymond E B Ketchum; Robert M Long; Rüdiger Kaspera; Mark R Wildung
Journal:  Phytochem Rev       Date:  2006-02       Impact factor: 5.374

4.  Administering cultured Taxus cells with early precursors reveals bifurcations in the taxoid biosynthetic pathway.

Authors:  Raymond E B Ketchum; Tohru Horiguchi; Deyou Qiu; Robert M Williams; Rodney B Croteau
Journal:  Phytochemistry       Date:  2006-12-08       Impact factor: 4.072

5.  The mass spectrometry of taxol.

Authors:  T D McClure; K H Schram; M L Reimer
Journal:  J Am Soc Mass Spectrom       Date:  1992-09       Impact factor: 3.109

Review 6.  Natural products synthesis: enabling tools to penetrate Nature's secrets of biogenesis and biomechanism.

Authors:  Robert M Williams
Journal:  J Org Chem       Date:  2011-04-12       Impact factor: 4.354

Review 7.  The early stages of taxol biosynthesis: an interim report on the synthesis and identification of early pathway metabolites.

Authors:  Jennifer Guerra-Bubb; Rodney Croteau; Robert M Williams
Journal:  Nat Prod Rep       Date:  2012-05-01       Impact factor: 13.423

8.  Synthesis and In Vitro Evaluation of Taxol oxetane ring D precursors.

Authors:  Rüdiger Kaspera; Jonathan L Cape; Juan A Faraldos; Raymond E B Ketchum; Rodney B Croteau
Journal:  Tetrahedron Lett       Date:  2010-04-14       Impact factor: 2.415

9.  Scalable enantioselective total synthesis of taxanes.

Authors:  Abraham Mendoza; Yoshihiro Ishihara; Phil S Baran
Journal:  Nat Chem       Date:  2011-11-06       Impact factor: 24.427

10.  Progress in nanotechnology based approaches to enhance the potential of chemopreventive agents.

Authors:  Irfana Muqbil; Ashiq Masood; Fazlul H Sarkar; Ramzi M Mohammad; Asfar S Azmi
Journal:  Cancers (Basel)       Date:  2011-01-21       Impact factor: 6.639
  10 in total

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