Literature DB >> 28853603

The BeSMART (Best Supportive Management for Adults Referred with Tonsillopharyngitis) multicentre observational study.

A S Lau1,2, C Mamais3,2, E McChesney1,2, N S Upile4,2, C Vaughan5,2, J Veitch6,2, J R Abbas7,2, A Markey8,2, N G Brown3,2, M Evans1,2, J Thomas1,2, M Gaines1,2, Z Shehata4, M D Wilkie2, S C Leong1,2.   

Abstract

Introduction Tonsillopharyngitis is the most common ear, nose and throat emergency admission, with 80,000 episodes recorded in England in 2015-2016. Despite this, there is a paucity of evidence addressing the supportive management of tonsillopharyngitis in inpatients. The aim of this retrospective multicentre observational study was to consider the Best Supportive Management for Adults Referred with Tonsillopharyngitis (BeSMART) in the inpatient setting, and to establish any associations between practice and outcomes. Methods Seven hospitals in North West England and North East Scotland participated in the study. Overall, 236 adult patients admitted with tonsillopharyngitis were included. The main outcome measures were interval to return to soft diet, length of stay (LOS), pain scores and readmissions. Results Women were more likely to seek professional help before presenting to secondary care (p=0.04). Patients admitted at the weekend were more likely to have a shorter LOS (p=0.03). There was no relationship between day of admission and seniority or specialty of the doctor initially seen. Prescription of corticosteroid, analgesia and a higher initial intravenous fluid infusion rate were not related to a shorter LOS. Conclusions This study is the first to yield valuable insights into the inpatient management of tonsillopharyngitis. This work represents part of an ongoing project to establish the evidence for common medical interventions for sore throat. Patient and professional surveys as well as a prospective interventional study are planned for the future.

Entities:  

Keywords:  Analgesia; Corticosteroid; Length of stay; Tonsillitis

Mesh:

Year:  2017        PMID: 28853603      PMCID: PMC5697044          DOI: 10.1308/rcsann.2017.0106

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  14 in total

1.  Aspirin compared with acetaminophen in the treatment of fever and other symptoms of upper respiratory tract infection in adults: a multicenter, randomized, double-blind, double-dummy, placebo-controlled, parallel-group, single-dose, 6-hour dose-ranging study.

Authors:  Claus Bachert; Alexander G Chuchalin; Reinhard Eisebitt; Vasiliy Z Netayzhenko; Michael Voelker
Journal:  Clin Ther       Date:  2005-07       Impact factor: 3.393

2.  Trainee-led research collaboratives: a novel model for delivering multi-centre studies.

Authors:  Aneel Bhangu; J Edward Fitzgerald; Angelos G Kolias
Journal:  ANZ J Surg       Date:  2014-12       Impact factor: 1.872

3.  Effect of chlorhexidine gluconate and benzydamine hydrochloride mouth spray on clinical signs and quality of life of patients with streptococcal tonsillopharyngitis: multicentre, prospective, randomised, double-blinded, placebo-controlled study.

Authors:  C Cingi; M Songu; A Ural; N Erdogmus; M Yildirim; H Cakli; C Bal
Journal:  J Laryngol Otol       Date:  2011-02-11       Impact factor: 1.469

4.  Effects of chlorhexidine/benzydamine mouth spray on pain and quality of life in acute viral pharyngitis: a prospective, randomized, double-blind, placebo-controlled, multicenter study.

Authors:  Cemal Cingi; Murat Songu; Ahmet Ural; Muzeyyen Yildirim; Nagehan Erdogmus; Cengiz Bal
Journal:  Ear Nose Throat J       Date:  2010-11       Impact factor: 1.697

Review 5.  Corticosteroids as standalone or add-on treatment for sore throat.

Authors:  Gail Hayward; Matthew J Thompson; Rafael Perera; Paul P Glasziou; Chris B Del Mar; Carl J Heneghan
Journal:  Cochrane Database Syst Rev       Date:  2012-10-17

6.  Out-patient management of patients with a peritonsillar abscess.

Authors:  C Al Yaghchi; A Cruise; K Kapoor; A Singh; J Harcourt
Journal:  Clin Otolaryngol       Date:  2008-02       Impact factor: 2.597

7.  Multicentre observational study of performance variation in provision and outcome of emergency appendicectomy.

Authors: 
Journal:  Br J Surg       Date:  2013-08       Impact factor: 6.939

8.  Promoting research and audit at medical school: evaluating the educational impact of participation in a student-led national collaborative study.

Authors:  Stephen J Chapman; James C D Glasbey; Chetan Khatri; Michael Kelly; Dmitri Nepogodiev; Aneel Bhangu; J Edward F Fitzgerald
Journal:  BMC Med Educ       Date:  2015-03-13       Impact factor: 2.463

Review 9.  Controversies in the management of acute tonsillitis: an evidence-based review.

Authors:  J H Bird; T C Biggs; E V King
Journal:  Clin Otolaryngol       Date:  2014-12       Impact factor: 2.597

10.  How to set up and manage a trainee-led research collaborative.

Authors:  George Dowswell; David C Bartlett; Kaori Futaba; Lisa Whisker; Thomas D Pinkney
Journal:  BMC Med Educ       Date:  2014-05-14       Impact factor: 2.463

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