Literature DB >> 28851030

Recent advances in analytical methods for the therapeutic drug monitoring of immunosuppressive drugs.

Yu Zhang1, Rui Zhang1.   

Abstract

Therapeutic drug monitoring (TDM) of immunosuppressive drugs (ISDs) with a narrow therapeutic index is an increasingly popular tool for minimizing drug toxicity while maximizing the prevention of graft loss and organ rejection. This review focuses on trends regarding analytical methods for the TDM of ISDs since 2011. The five most commonly prescribed immunosuppressive medications are critically reviewed: cyclosporine A, tacrolimus, sirolimus (rapamycin), everolimus, and mycophenolic acid. This review introduces the general background of TDM and ISDs and presents the recent developments in using liquid chromatography-tandem mass spectrometry (LC-MS/MS) and immunoassays for the TDM of ISDs. Finally, a future perspective for these analytical methods is briefly discussed.
Copyright © 2017 John Wiley & Sons, Ltd.

Entities:  

Keywords:  Immunoassay; Immunosuppressive drugs; Liquid chromatography; Mass spectrometry; Therapeutic drug monitoring

Mesh：

Substances：

Year:  2017        PMID： 28851030     DOI： 10.1002/dta.2290

Source DB:  PubMed          Journal:  Drug Test Anal        ISSN： 1942-7603            Impact factor:   3.345


  14 in total

1.  Feasibility of Using High-Contrast Grating as a Point-of-Care Sensor for Therapeutic Drug Monitoring of Immunosuppressants.

Authors:  Yi-Cheng Liu; Christina Thantrakul; Shu Kan; Connie Chang-Hasnain; Dong-Ru Ho
Journal:  IEEE J Transl Eng Health Med       Date:  2020-01-30       Impact factor: 3.316

Review 2.  Review of Chromatographic Methods Coupled with Modern Detection Techniques Applied in the Therapeutic Drugs Monitoring (TDM).

Authors:  Tomasz Tuzimski; Anna Petruczynik
Journal:  Molecules       Date:  2020-09-03       Impact factor: 4.411

Review 3.  Therapeutic Drug Monitoring of Antidepressants: An Underused but Potentially Valuable Tool in Primary Care.

Authors:  Daria Piacentino; Esperia Bianchi; Domenico De Donatis; Vincenzo Florio; Andreas Conca
Journal:  Front Psychiatry       Date:  2022-03-29       Impact factor: 4.157

Review 4.  Therapeutic Drug Monitoring Is a Feasible Tool to Personalize Drug Administration in Neonates Using New Techniques: An Overview on the Pharmacokinetics and Pharmacodynamics in Neonatal Age.

Authors:  Domenico Umberto De Rose; Sara Cairoli; Marco Dionisi; Alessandra Santisi; Luca Massenzi; Bianca Maria Goffredo; Carlo Dionisi-Vici; Andrea Dotta; Cinzia Auriti
Journal:  Int J Mol Sci       Date:  2020-08-17       Impact factor: 5.923

5.  Immunosuppressive Drug Measurement by Liquid Chromatography Coupled to Tandem Mass Spectrometry: Interlaboratory Comparison in the Korean Clinical Laboratories.

Authors:  Hyun-Ki Kim; Hyung-Doo Park; Sang-Guk Lee; Hyojin Chae; Sang Hoon Song; Yong-Wha Lee; Yeo-Min Yun; Sunhyun Ahn; Serim Kim; Sun Min Lee; Soo-Youn Lee; Sail Chun
Journal:  Ann Lab Med       Date:  2021-05-01       Impact factor: 3.464

6.  Validation of a simple liquid chromatography coupled to tandem mass spectrometry method for the simultaneous determination of tacrolimus, sirolimus, everolimus and cyclosporin A in dried matrix on paper discs.

Authors:  Ignacio Guillermo Bressán; María Isabel Giménez; Susana Francisca Llesuy
Journal:  J Mass Spectrom Adv Clin Lab       Date:  2021-02-02

7.  Validated Simple HPLC-UV Method for Mycophenolic Acid (MPA) Monitoring in Human Plasma. Internal Standardization: Is It Necessary?

Authors:  Paweł K Kunicki; Aleksandra Wróbel
Journal:  Molecules       Date:  2021-11-29       Impact factor: 4.411

8.  Editorial: Therapeutic Drug Monitoring in Solid Organ Transplantation.

Authors:  Christine E Staatz; Nicole M Isbel; Troels K Bergmann; Bente Jespersen; Niels Henrik Buus
Journal:  Front Pharmacol       Date:  2021-12-10       Impact factor: 5.810

9.  Fully Automated Quantitative Measurement of Serum Organic Acids via LC-MS/MS for the Diagnosis of Organic Acidemias: Establishment of an Automation System and a Proof-of-Concept Validation.

Authors:  Yasushi Ueyanagi; Daiki Setoyama; Daisuke Kawakami; Yuichi Mushimoto; Shinya Matsumoto; Taeko Hotta; Dongchon Kang
Journal:  Diagnostics (Basel)       Date:  2021-11-25

Review 10.  Mass spectrometry based high-throughput bioanalysis of low molecular weight compounds: are we ready to support personalized medicine?

Authors:  Sophie Bravo-Veyrat; Gérard Hopfgartner
Journal:  Anal Bioanal Chem       Date:  2021-08-23       Impact factor: 4.142
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