Literature DB >> 28850146

The importance of asking "how and why?" in natural product structure elucidation.

Patrick D Brown1, Andrew L Lawrence.   

Abstract

Covering: up to 2017This review highlights why careful consideration of the biosynthetic origin (the how) and the biological function (the why) of a natural product can be so useful during the determination of its structure. Recent examples of structural reassignments inspired by biosynthetic and functional insights will be presented. This review will demonstrate the importance of viewing the origin, structure and function of a natural product as intertwined threads of a single story, best viewed as a whole rather than as discrete topics.

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Year:  2017        PMID： 28850146     DOI： 10.1039/c7np00025a

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  8 in total

Review 1.  Recent trends in the structural revision of natural products.

Authors:  Bhuwan Khatri Chhetri; Serge Lavoie; Anne Marie Sweeney-Jones; Julia Kubanek
Journal:  Nat Prod Rep       Date:  2018-06-20       Impact factor: 13.423

Review 2.  Deep-Sea Natural Products from Extreme Environments: Cold Seeps and Hydrothermal Vents.

Authors:  Mengjing Cong; Xiaoyan Pang; Kai Zhao; Yue Song; Yonghong Liu; Junfeng Wang
Journal:  Mar Drugs       Date:  2022-06-19       Impact factor: 6.085

3.  Bioinspired Total Synthesis of Erectones A and B, and the Revised Structure of Hyperelodione D.

Authors:  Liam J Franov; Jacob D Hart; Glenn A Pullella; Christopher J Sumby; Jonathan H George
Journal:  Angew Chem Int Ed Engl       Date:  2022-03-14       Impact factor: 16.823

4.  Puzzling Out the Structure of Novofumigatamide: Total Synthesis of Constitutional Isomers. Part II.

Authors:  Patricia García-Domínguez; Angel R de Lera
Journal:  J Org Chem       Date:  2022-09-21       Impact factor: 4.198

Review 5.  The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research.

Authors:  James B McAlpine; Shao-Nong Chen; Andrei Kutateladze; John B MacMillan; Giovanni Appendino; Andersson Barison; Mehdi A Beniddir; Maique W Biavatti; Stefan Bluml; Asmaa Boufridi; Mark S Butler; Robert J Capon; Young H Choi; David Coppage; Phillip Crews; Michael T Crimmins; Marie Csete; Pradeep Dewapriya; Joseph M Egan; Mary J Garson; Grégory Genta-Jouve; William H Gerwick; Harald Gross; Mary Kay Harper; Precilia Hermanto; James M Hook; Luke Hunter; Damien Jeannerat; Nai-Yun Ji; Tyler A Johnson; David G I Kingston; Hiroyuki Koshino; Hsiau-Wei Lee; Guy Lewin; Jie Li; Roger G Linington; Miaomiao Liu; Kerry L McPhail; Tadeusz F Molinski; Bradley S Moore; Joo-Won Nam; Ram P Neupane; Matthias Niemitz; Jean-Marc Nuzillard; Nicholas H Oberlies; Fernanda M M Ocampos; Guohui Pan; Ronald J Quinn; D Sai Reddy; Jean-Hugues Renault; José Rivera-Chávez; Wolfgang Robien; Carla M Saunders; Thomas J Schmidt; Christoph Seger; Ben Shen; Christoph Steinbeck; Hermann Stuppner; Sonja Sturm; Orazio Taglialatela-Scafati; Dean J Tantillo; Robert Verpoorte; Bin-Gui Wang; Craig M Williams; Philip G Williams; Julien Wist; Jian-Min Yue; Chen Zhang; Zhengren Xu; Charlotte Simmler; David C Lankin; Jonathan Bisson; Guido F Pauli
Journal:  Nat Prod Rep       Date:  2018-07-13       Impact factor: 13.423

6.  Cyclodepsipeptide alveolaride C: total synthesis and structural assignment.

Authors:  Sanu Saha; Debobrata Paul; Rajib Kumar Goswami
Journal:  Chem Sci       Date:  2020-09-21       Impact factor: 9.825

7.  Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS).

Authors:  Sonja L Knowles; Ngoc Vu; Daniel A Todd; Huzefa A Raja; Antonis Rokas; Qibin Zhang; Nicholas H Oberlies
Journal:  J Nat Prod       Date:  2019-12-11       Impact factor: 4.803

Review 8.  Recent Achievements in Total Synthesis for Integral Structural Revisions of Marine Natural Products.

Authors:  Min Woo Ha; Jonghoon Kim; Seung-Mann Paek
Journal:  Mar Drugs       Date:  2022-02-25       Impact factor: 5.118
  8 in total

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