Literature DB >> 28847758

Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications.

Pawan K Mishra1, Harshita Mishra2, Adam Ekielski3, Sushama Talegaonkar2, Bhuvaneshwar Vaidya4.   

Abstract

Zinc oxide (ZnO) nanoparticles (NPs) are a promising platform for use in biomedical research, especially given their anticancer and antimicrobial activities. These activities are associated with the ability of ZnO NPs to generate reactive oxygen species (ROS) and induce apoptosis. In addition, ZnO NPs have been successfully exploited as drug carriers for loading and transporting drugs to target sites, thereby reducing unwanted toxicity and off-target effects, and resulting in amplified synergistic effects. Here, we discuss the synthesis and biomedical applications of ZnO NPs.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 28847758     DOI: 10.1016/j.drudis.2017.08.006

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN: 1359-6446            Impact factor:   7.851


  75 in total

1.  Induction of necrotic cell death and activation of STING in the tumor microenvironment via cationic silica nanoparticles leading to enhanced antitumor immunity.

Authors:  Myunggi An; Chunsong Yu; Jingchao Xi; Joyce Reyes; Guangzhao Mao; Wei-Zen Wei; Haipeng Liu
Journal:  Nanoscale       Date:  2018-05-17       Impact factor: 7.790

Review 2.  Zinc-Based Biomaterials for Regeneration and Therapy.

Authors:  Yingchao Su; Irsalan Cockerill; Yadong Wang; Yi-Xian Qin; Lingqian Chang; Yufeng Zheng; Donghui Zhu
Journal:  Trends Biotechnol       Date:  2018-11-21       Impact factor: 19.536

3.  Age-related physicochemical differences in ZnO nanoparticles in the seawater and their bacterial interaction.

Authors:  Asli Baysal; Hasan Saygin; Gul Sirin Ustabasi
Journal:  Environ Monit Assess       Date:  2020-04-10       Impact factor: 2.513

4.  Exploration of immunomodulatory and protective effect of Withania somnifera on trace metal oxide (zinc oxide nanoparticles) induced toxicity in Balb/c mice.

Authors:  Jitendra Kumar; Murli Dhar Mitra; Ahmad Hussain; Gautam Kaul
Journal:  Mol Biol Rep       Date:  2019-03-07       Impact factor: 2.316

5.  Translating Nanomedicine to Comparative Oncology-the Case for Combining Zinc Oxide Nanomaterials with Nucleic Acid Therapeutic and Protein Delivery for Treating Metastatic Cancer.

Authors:  R K DeLong; Yi-Hsien Cheng; Paige Pearson; Zhoumeng Lin; Calli Coffee; Elza Neelima Mathew; Amanda Hoffman; Raelene M Wouda; Mary Lynn Higginbotham
Journal:  J Pharmacol Exp Ther       Date:  2019-04-30       Impact factor: 4.030

Review 6.  Phytosynthesized metal oxide nanoparticles for pharmaceutical applications.

Authors:  Swetha Andra; Satheesh Kumar Balu; Jaison Jeevanandham; Murugesan Muthalagu; Manisha Vidyavathy; Yen San Chan; Michael Kobina Danquah
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2019-05-17       Impact factor: 3.000

7.  Microfluidics-enabled rational design of ZnO micro-/nanoparticles with enhanced photocatalysis, cytotoxicity, and piezoelectric properties.

Authors:  Nanjing Hao; Zhe Xu; Yuan Nie; Congran Jin; Andrew B Closson; Michael Zhang; John X J Zhang
Journal:  Chem Eng J       Date:  2019-07-12       Impact factor: 13.273

Review 8.  Microfluidics for ZnO micro-/nanomaterials development: rational design, controllable synthesis, and on-chip bioapplications.

Authors:  Nanjing Hao; Michael Zhang; John X J Zhang
Journal:  Biomater Sci       Date:  2020-03-31       Impact factor: 6.843

9.  Toxicity of combined exposure of ZnO nanoparticles (NPs) and myricetin to Caco-2 cells: changes of NP colloidal aspects, NP internalization and the apoptosis-endoplasmic reticulum stress pathway.

Authors:  Chaohua Wu; Yunfeng Luo; Liangliang Liu; Yixi Xie; Yi Cao
Journal:  Toxicol Res (Camb)       Date:  2019-06-20       Impact factor: 3.524

10.  MTH1 is involved in the toxic and carcinogenic long-term effects induced by zinc oxide and cobalt nanoparticles.

Authors:  Irene Barguilla; Gabriela Barszczewska; Balasubramanyam Annangi; Josefa Domenech; Antonia Velázquez; Ricard Marcos; Alba Hernández
Journal:  Arch Toxicol       Date:  2020-05-06       Impact factor: 5.153

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