Literature DB >> 28847707

Updating knowledge on new medically important scorpion species in Mexico.

Lidia Riaño-Umbarila1, Everardo R Rodríguez-Rodríguez2, Carlos E Santibañez-López3, Leopoldo Güereca4, Selene J Uribe-Romero5, Ilse V Gómez-Ramírez6, Edson N Cárcamo-Noriega7, Lourival D Possani8, Baltazar Becerril9.   

Abstract

The increment in the number of scorpion envenoming cases in Mexico is mainly associated to the rapid growth of the urban areas, and consequently, to the invasion of natural habitats of these arachnids. On the other hand, there is a great diversity of scorpion species, so it is indispensable to identify those of medical importance, which we now know are many more than the 7-8 previously reported as dangerous to humans. Because different LD50 values have been reported for the venom of the same species, probably due to variations in the experimental conditions used, in this work we determined the LD50 values for the venoms of 13 different species of scorpions using simple but systematic procedures. This information constitutes a referent on the level of toxicity of medically important scorpion species from Mexico and establishes the bases for a more comprehensive assessment of the neutralizing capacity of current and developing antivenoms.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Lethal doses; New poisonous scorpions; Toxicity

Mesh:

Substances:

Year:  2017        PMID: 28847707     DOI: 10.1016/j.toxicon.2017.08.022

Source DB:  PubMed          Journal:  Toxicon        ISSN: 0041-0101            Impact factor:   3.033


  5 in total

1.  Characterization of Four Medically Important Toxins from Centruroides huichol Scorpion Venom and Its Neutralization by a Single Recombinant Antibody Fragment.

Authors:  Hugo Valencia-Martínez; Timoteo Olamendi-Portugal; Rita Restano-Cassulini; Hugo Serrano-Posada; Fernando Zamudio; Lourival D Possani; Lidia Riaño-Umbarila; Baltazar Becerril
Journal:  Toxins (Basel)       Date:  2022-05-26       Impact factor: 5.075

2.  Mass fingerprinting and electrophysiological analysis of the venom from the scorpion Centruroides hirsutipalpus (Scorpiones: Buthidae).

Authors:  Laura L Valdez-Velázquez; Timoteo Olamendi-Portugal; Rita Restano-Cassulini; Fernando Z Zamudio; Lourival D Possani
Journal:  J Venom Anim Toxins Incl Trop Dis       Date:  2018-07-03

3.  Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms.

Authors:  Lidia Riaño-Umbarila; Ilse V Gómez-Ramírez; Luis M Ledezma-Candanoza; Timoteo Olamendi-Portugal; Everardo Remi Rodríguez-Rodríguez; Guillermo Fernández-Taboada; Lourival D Possani; Baltazar Becerril
Journal:  Toxins (Basel)       Date:  2019-01-10       Impact factor: 4.546

4.  Full Neutralization of Centruroidessculpturatus Scorpion Venom by Combining Two Human Antibody Fragments.

Authors:  Lidia Riaño-Umbarila; José Alberto Romero-Moreno; Luis M Ledezma-Candanoza; Timoteo Olamendi-Portugal; Lourival D Possani; Baltazar Becerril
Journal:  Toxins (Basel)       Date:  2021-10-06       Impact factor: 4.546

5.  Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879).

Authors:  Jimena I Cid-Uribe; Erika P Meneses; Cesar V F Batista; Ernesto Ortiz; Lourival D Possani
Journal:  Toxins (Basel)       Date:  2019-04-30       Impact factor: 4.546

  5 in total

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