Literature DB >> 28843943

Evaluation of contact precautions for methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus.

Ana Cecilia Bardossy1, Muhammad Yasser Alsafadi2, Patricia Starr3, Eman Chami3, Jennifer Pietsch3, Daniela Moreno1, Laura Johnson1, George Alangaden4, Marcus Zervos4, Katherine Reyes5.   

Abstract

BACKGROUND: There are limited controlled data demonstrating contact precautions (CPs) prevent methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) infections in endemic settings. We evaluated changes in hospital-acquired MRSA and VRE infections after discontinuing CPs for these organisms.
METHODS: This is a retrospective study done at an 800-bed teaching hospital in urban Detroit. CPs for MRSA and VRE were discontinued hospital-wide in 2013. Data on MRSA and VRE catheter-associated urinary tract infections (CAUTIs), ventilator-associated pneumonia (VAP), central line-associated bloodstream infections (CLABSIs), surgical site infections (SSIs), and hospital-acquired MRSA bacteremia (HA-MRSAB) rates were compared before and after CPs discontinuation.
RESULTS: There were 36,907 and 40,439 patients hospitalized during the two 12-month periods: CPs and no CPs. Infection rates in the CPs and no-CPs periods were as follows: (1) MRSA infections: VAP, 0.13 versus 0.11 (P = .84); CLABSI, 0.11 versus 0.19 (P = .45); SSI, 0 versus 0.14 (P = .50); and CAUTI, 0.025 versus 0.033 (P = .84); (2) VRE infections: CAUTI, 0.27 versus 0.13 (P = .19) and CLABSI, 0.29 versus 0.3 (P = .94); and (3) HA-MRSAB rates: 0.14 versus 0.11 (P = .55), respectively.
CONCLUSIONS: Discontinuation of CPs did not adversely impact endemic MRSA and VRE infection rates.
Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Contact precautions; Methicillin-resistant Staphylococcus aureus; Vancomycin-resistant Enterococcus

Mesh:

Year:  2017        PMID: 28843943     DOI: 10.1016/j.ajic.2017.06.017

Source DB:  PubMed          Journal:  Am J Infect Control        ISSN: 0196-6553            Impact factor:   2.918


  3 in total

Review 1.  Vancomycin-resistant enterococci (VRE): a reason to isolate?

Authors:  Maria J G T Vehreschild; Miriam Haverkamp; Lena M Biehl; Sebastian Lemmen; Gerd Fätkenheuer
Journal:  Infection       Date:  2018-09-03       Impact factor: 3.553

Review 2.  Antibiotic stewardship and horizontal infection control are more effective than screening, isolation and eradication.

Authors:  S W Lemmen; K Lewalter
Journal:  Infection       Date:  2018-05-23       Impact factor: 3.553

Review 3.  Vancomycin-resistant enterococcus infection in the hematopoietic stem cell transplant recipient: an overview of epidemiology, management, and prevention.

Authors:  Esther Benamu; Stanley Deresinski
Journal:  F1000Res       Date:  2018-01-02
  3 in total

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