Palladium nanoparticles embedded on mesoporous TiO2 material (Pd@MTiO2) as an efficient heterogeneous catalyst for Suzuki-Coupling reactions in water medium.

An efficient and recyclable catalytic system composed of palladium nanoparticles embedded over mesoporous TiO2 material (Pd@MTiO2) has been synthesized and its catalytic activity has been explored in Suzuki-Miyaura cross-coupling reaction of aryl halides in water medium. This catalytic system is a very simple and highly active protocol for carrying out the Suzuki coupling of aryl bromide and aryl chloride with boronic acids, which proceed smoothly in excellent yields under mild reaction conditions. Powder X-ray diffraction (XRD), transmission electron microscopy (TEM), energy-dispersive X-ray spectroscopy (EDX), Fourier transform infrared spectroscopy (FT-IR), and N2 sorption studies are used to characterize the Pd@MTiO2 material. Environmentally friendly reaction conditions, high product yield, tolerance of variety of functionalities in the reactants and reusability suggested future potential of Pd@MTiO2 for the synthesis of a wide range of biaryl compounds.