Literature DB >> 28843849

Contamination incidents in the pre-analytical phase of forensic DNA analysis in Austria-Statistics of 17 years.

Ines Pickrahn1, Gabriele Kreindl1, Eva Müller1, Bettina Dunkelmann1, Waltraud Zahrer1, Jan Cemper-Kiesslich1, F Neuhuber2.   

Abstract

Forensic DNA analyses have become more and more sensitive in the past years. With the ability to generate DNA profiles even from minute amounts of cellular material also the possibility to detect DNA on trace material that originates from persons not linked to the crime event, such as crime scene investigators, increases. The contamination of crime scene samples can lead to false positive results and misinterpretation that can cause deceptive investigations. In this work we continue a study of 2010 that compared the number of detected contamination incidents that were caused in the pre-analytical phase of forensic DNA analysis with the number of crime scene samples analyzed by our laboratory. Within the past 17 years we were able to detect a total of 347 contamination incidents caused by police officers in approximately 46,000 trace samples to their origin (0.75%). Additionally we demonstrate the usefulness of reference profile databases that contain DNA profiles of police officers to detect contamination incidents of trace material.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Contamination; Forensic DNA analysis; Police Elimination Database (PED); Profile comparison

Mesh:

Year:  2017        PMID: 28843849     DOI: 10.1016/j.fsigen.2017.07.012

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


  2 in total

Review 1.  Interpol review of forensic biology and forensic DNA typing 2016-2019.

Authors:  John M Butler; Sheila Willis
Journal:  Forensic Sci Int       Date:  2020-02-20       Impact factor: 2.395

2.  A fast, reliable and easy method to detect within-species DNA contamination.

Authors:  Tiziano Dallavilla; Giuseppe Marceddu; Arianna Casadei; Luca De Antoni; Matteo Bertelli
Journal:  Acta Biomed       Date:  2020-11-09
  2 in total

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