Literature DB >> 28841601

Prophylactic Nipple-Sparing Mastectomy and Direct-to-Implant Reconstruction of the Large and Ptotic Breast: Is Preshaping of the Challenging Breast a Key to Success?

Gudjon L Gunnarsson1, Camilla Bille, Laurens C Reitsma, Peter Wamberg, Jørn Bo Thomsen.   

Abstract

BACKGROUND: Nipple-sparing mastectomy with simultaneous hammock technique direct-to-implant reconstruction is increasingly offered to patients opting for risk-reducing mastectomy. Despite this promising method, patients with macromastia and ptotic breasts remain a challenging group to treat satisfactorily and more often end up undergoing a difficult corrective procedure and experience an unacceptably high rate of failed reconstruction. The authors examined whether targeted preshaping mastopexy/reduction could prepare these patients for a successful nipple-sparing mastectomy/direct-to-implant reconstruction.
METHODS: Patients seeking risk-reducing nipple-sparing mastectomy/direct-to-implant reconstruction at the authors' institutions deemed unfit for a one-stage procedure based on their previous experience were offered a targeted two-stage, risk-reducing mastopexy/reduction followed by a delayed secondary nipple-sparing mastectomy and direct-to-implant reconstruction. Patients were followed up at 3 weeks and 6 or 12 months.
RESULTS: Forty-four reconstructions were performed in 22 patients aged 43 years (range, 26 to 57 years). All 44 procedures were completed successfully without any failure or nipple-areola complex losses. Patients' median body mass index was 30 kg/m (range, 22 to 44 kg/m). Six patients were smokers and one had hypertension. Two patients underwent reoperation because of hematoma and fat necrosis.
CONCLUSIONS: The authors' results demonstrate that a targeted preshaping mastopexy/reduction followed by nipple-sparing mastectomy/direct-to-implant reconstruction can be safely planned in women who opt for a risk-reducing mastectomy and can be performed successfully with a 3- to 4-month time span between operations. On the basis of these results and the superior cosmetic outcome, the two-stage approach has become the authors' standard of care in all such settings. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

Entities:  

Mesh:

Year:  2017        PMID: 28841601     DOI: 10.1097/PRS.0000000000003621

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  10 in total

1.  Visualized immediate breast reconstruction with dermal flap and implant.

Authors:  Lena Carstensen
Journal:  Gland Surg       Date:  2019-10

2.  Visualized pre- and subpectoral implant placement for immediate breast reconstruction.

Authors:  Diana L Dyrberg; Camilla Bille; Gudjon L Gunnarsson; Jens A Sørensen; Jørn B Thomsen
Journal:  Gland Surg       Date:  2019-10

3.  Identifying the dissection plane for mastectomy-description and visualization of our technique.

Authors:  Camilla Bille; Farima Dalaei; Jørn Bo Thomsen
Journal:  Gland Surg       Date:  2019-10

Review 4.  Update in Direct-to-Implant Breast Reconstruction.

Authors:  Aurelia Trisliana Perdanasari; Amjed Abu-Ghname; Sarth Raj; Sebastian J Winocour; Rene D Largo
Journal:  Semin Plast Surg       Date:  2019-10-17       Impact factor: 2.314

5.  Delayed two-stage nipple sparing mastectomy and simultaneous expander-to-implant reconstruction of the large and ptotic breast.

Authors:  Thierry Tondu; Filip Thiessen; Guy Hubens; Wiebren Tjalma; Phillip Blondeel; Veronique Verhoeven
Journal:  Gland Surg       Date:  2022-03

6.  Risk Comparison Using Autologous Dermal Flap and Absorbable Breast Mesh on Patient Undergoing Subcutaneous Mastectomy with Immediate Breast Reconstruction.

Authors:  Matej Patzelt; Lucie Zarubova; Michaela Vecerova; Josef Barta; Martin Ouzky; Andrej Sukop
Journal:  Aesthetic Plast Surg       Date:  2022-02-14       Impact factor: 2.708

Review 7.  Implant-Based Breast Reconstruction after Mastectomy, from the Subpectoral to the Prepectoral Approach: An Evidence-Based Change of Mind?

Authors:  Andrea Weinzierl; Daniel Schmauss; Davide Brucato; Yves Harder
Journal:  J Clin Med       Date:  2022-05-30       Impact factor: 4.964

8.  Prepectoral Hammock and Direct-to-implant Breast Reconstruction in 10 Minutes: A Focus on Technique.

Authors:  Gudjon L Gunnarsson; Jorn Bo Thomsen
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-10-02

9.  Research trends and performances of breast reconstruction: a bibliometric analysis.

Authors:  Yunzhu Li; Xiaojun Wang; Jørn Bo Thomsen; Maurice Y Nahabedian; Naohiro Ishii; Warren M Rozen; Xiao Long; Yuh-Shan Ho
Journal:  Ann Transl Med       Date:  2020-11

Review 10.  Oncoplastic Breast Consortium consensus conference on nipple-sparing mastectomy.

Authors:  Walter P Weber; Martin Haug; Christian Kurzeder; Vesna Bjelic-Radisic; Rupert Koller; Roland Reitsamer; Florian Fitzal; Jorge Biazus; Fabricio Brenelli; Cicero Urban; Régis Resende Paulinelli; Jens-Uwe Blohmer; Jörg Heil; Jürgen Hoffmann; Zoltan Matrai; Giuseppe Catanuto; Viviana Galimberti; Oreste Gentilini; Mitchel Barry; Tal Hadar; Tanir M Allweis; Oded Olsha; Maria João Cardoso; Pedro F Gouveia; Isabel T Rubio; Jana de Boniface; Tor Svensjö; Susanne Bucher; Peter Dubsky; Jian Farhadi; Mathias K Fehr; Ilario Fulco; Ursula Ganz-Blättler; Andreas Günthert; Yves Harder; Nik Hauser; Elisabeth A Kappos; Michael Knauer; Julia Landin; Robert Mechera; Francesco Meani; Giacomo Montagna; Mathilde Ritter; Ramon Saccilotto; Fabienne D Schwab; Daniel Steffens; Christoph Tausch; Jasmin Zeindler; Savas D Soysal; Visnu Lohsiriwat; Tibor Kovacs; Anne Tansley; Lynda Wyld; Laszlo Romics; Mahmoud El-Tamer; Andrea L Pusic; Virgilio Sacchini; Michael Gnant
Journal:  Breast Cancer Res Treat       Date:  2018-09-04       Impact factor: 4.872

  10 in total

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