Alberto A Uribe1, Ehud Mendel2, Zoe A Peters3, Bassel F Shneker4, Mahmoud Abdel-Rasoul5, Sergio D Bergese6. 1. The Ohio State University Wexner Medical Center, Department of Anesthesiology, Columbus, OH, USA. Electronic address: alberto.uribe@osumc.edu. 2. The Ohio State University Wexner Medical Center, Department of Neurological Surgery, Columbus, OH, USA. 3. The Ohio State University Wexner Medical Center, Department of Anesthesiology, Columbus, OH, USA. 4. Biotronic Neuro Network, Ann Arbor, MI, USA. 5. The Ohio State University, Center of Biostatistics, Columbus, OH, USA. 6. The Ohio State University Wexner Medical Center, Department of Anesthesiology, Columbus, OH, USA; The Ohio State University Wexner Medical Center, Department of Neurological Surgery, Columbus, OH, USA.
Abstract
OBJECTIVE: To determine the comparison of its clinical utility and safety profile for visual evoked potential (VEP) monitoring during prone spine surgeries under totalintravenous anesthesia (TIVA) versus balanced general anesthesia using the SightSaver™ visual stimulator. METHODS: The protocol was designed asa pilot, single center, prospective, randomized, and double-arm study. Subjects were randomized to receive either TIVA or balanced general anesthesia. Following induction and intubation, 8 electrodes were placed subcutaneously to collect VEP recordings. The SightSaver™ visual stimulator was placed on the subject's scalp before prone positioning. VEP waveforms were recorded every 30min and assessed by a neurophysiologist throughout the length of surgery. RESULTS:A total of 19 subjects were evaluated and VEP waveforms were successfully collected. TIVA group showed higher amplitude and lower latency than balanced anesthesia. CONCLUSIONS: Our data suggested that TIVA is associated with higher VEP amplitude and shorter latencies than balanced general anesthesia; therefore, TIVA could be the most efficient anesthesia regimen for VEP monitoring. SIGNIFICANCE: The findings help to better understand the effect of different anesthesia regimens on intra-operative VEP monitoring.
RCT Entities:
OBJECTIVE: To determine the comparison of its clinical utility and safety profile for visual evoked potential (VEP) monitoring during prone spine surgeries under total intravenous anesthesia (TIVA) versus balanced general anesthesia using the SightSaver™ visual stimulator. METHODS: The protocol was designed asa pilot, single center, prospective, randomized, and double-arm study. Subjects were randomized to receive either TIVA or balanced general anesthesia. Following induction and intubation, 8 electrodes were placed subcutaneously to collect VEP recordings. The SightSaver™ visual stimulator was placed on the subject's scalp before prone positioning. VEP waveforms were recorded every 30min and assessed by a neurophysiologist throughout the length of surgery. RESULTS: A total of 19 subjects were evaluated and VEP waveforms were successfully collected. TIVA group showed higher amplitude and lower latency than balanced anesthesia. CONCLUSIONS: Our data suggested that TIVA is associated with higher VEP amplitude and shorter latencies than balanced general anesthesia; therefore, TIVA could be the most efficient anesthesia regimen for VEP monitoring. SIGNIFICANCE: The findings help to better understand the effect of different anesthesia regimens on intra-operative VEP monitoring.
Authors: José Antonio Soriano Sánchez; Kai Uwe Lewandrowski; José Alfonso Franco Jímenez; Manuel Eduardo Soto Garcia; Sergio Soriano Solís; Manuel Rodríguez García; Oscar Sanchéz Escandón; José Alberto Israel Romero Rangel Journal: Int J Spine Surg Date: 2021-09-22