Literature DB >> 28836198

Mouse Models of Corneal Scarring.

Laure Rittié1,2, Audrey E K Hutcheon3, James D Zieske4.   

Abstract

Corneal scarring is an obligatory consequence of stroma corneal injury and is a major cause of decreased visual quality and vision loss worldwide. There are currently no satisfactory intervention therapies for corneal fibrosis. In this chapter, we describe well-established in vivo corneal wound models to allow researchers to investigate epithelial and stromal responses to corneal injury.

Entities:  

Keywords:  Cornea; Epithelial debridement; Incision; Keratectomy; Mouse

Mesh:

Year:  2017        PMID: 28836198     DOI: 10.1007/978-1-4939-7113-8_8

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


  4 in total

1.  Animal and Human Models of Tissue Repair and Fibrosis: An Introduction.

Authors:  David Lagares; Boris Hinz
Journal:  Methods Mol Biol       Date:  2021

2.  BRD4 inhibitor JQ1 inhibits and reverses mechanical injury-induced corneal scarring.

Authors:  Mingli Qu; Xiaoping Zhang; Xiaoli Hu; Muchen Dong; Xiaojing Pan; Jiang Bian; Qingjun Zhou
Journal:  Cell Death Discov       Date:  2018-06-28

3.  Netrin-1 promotes epithelium repair in corneal injury.

Authors:  Yun Han; Nan Jiang; Ting Su; Qi-Chen Yang; Cong-Cong Yan; Lei Ye; Qing Yuan; Pei-Wen Zhu; Wei Li; Zu-Guo Liu; Yi Shao
Journal:  Int J Ophthalmol       Date:  2020-02-18       Impact factor: 1.779

4.  Biology of corneal fibrosis: soluble mediators, integrins, and extracellular vesicles.

Authors:  Tina B McKay; Audrey E K Hutcheon; James D Zieske
Journal:  Eye (Lond)       Date:  2019-12-12       Impact factor: 3.775

  4 in total

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