Umesh Chandra Behera1, Rohit R Modi2, Jenil Sheth2, Arshi Singh2. 1. L V Prasad Eye Institute, Patia, Bhubaneswar, Odisha, 751024, India. umeshcbehera@gmail.com. 2. L V Prasad Eye Institute, Patia, Bhubaneswar, Odisha, 751024, India.
Abstract
PURPOSE: To report a case of macular infarction after doublet chemotherapy with gemcitabine and carboplatin. METHODS: A middle-aged lady presenting with bilateral macular infarction post-chemotherapy for metastatic cervical malignancy was investigated for thromboembolic risks and treated. RESULTS: The macular perfusion and edema improved with control of hypertension and treatment with pentoxifylline. Visual improvement was satisfactory, and the possible associated risk such as hypertension was noted. CONCLUSION: This case underscores the need for active screening of patients on chemotherapy with gemcitabine and carboplatin for retinal vascular occlusive changes when hypertension is associated.
PURPOSE: To report a case of macular infarction after doublet chemotherapy with gemcitabine and carboplatin. METHODS: A middle-aged lady presenting with bilateral macular infarction post-chemotherapy for metastatic cervical malignancy was investigated for thromboembolic risks and treated. RESULTS: The macular perfusion and edema improved with control of hypertension and treatment with pentoxifylline. Visual improvement was satisfactory, and the possible associated risk such as hypertension was noted. CONCLUSION: This case underscores the need for active screening of patients on chemotherapy with gemcitabine and carboplatin for retinal vascular occlusive changes when hypertension is associated.
Authors: Daniel Souza Monteiro de Araújo; Rafael Brito; Danniel Pereira-Figueiredo; Alexandre Dos Santos-Rodrigues; Francesco De Logu; Romina Nassini; Andrea Zin; Karin C Calaza Journal: Int J Mol Sci Date: 2022-07-25 Impact factor: 6.208