Literature DB >> 28835076

[Current treatment in advanced hepatocellular carcinoma and prospects for immuno-oncology therapy].

J M Xu1.   

Abstract

Treatment of patients with advanced hepatocellular carcinoma (HCC) remains a huge challenge since a widely accepted therapeutic strategy has not been identified. There are some special features in patients with HCC in China, such as are mainly related to hepatitis B virus infection, often diagnosed as advanced or end-stage disease, and usually have a poorer prognosis compared with patients in western countries. Hence, appropriate treatments are urgently needed for these patients. Notably, immune-oncology therapy has been received increased attention in recent years. Based on promising results observed in clinical trials, immune-oncology therapy has been approved for treatment of various malignant diseases and brings a new hope to the treatment of advanced HCC. The review summarizes the current situation of advanced HCC treatment in China and discusses the prospects of immuno-oncology therapy.

Entities:  

Keywords:  Immune Checkpoint Inhibitor; Immuno-Oncology Therapy; Neoplasms, hepatocellular

Mesh:

Year:  2017        PMID: 28835076     DOI: 10.3760/cma.j.issn.0253-3766.2017.08.001

Source DB:  PubMed          Journal:  Zhonghua Zhong Liu Za Zhi        ISSN: 0253-3766


  3 in total

1.  LncRNA NUTM2A-AS1 aggravates the progression of hepatocellular carcinoma by activating the miR-186-5p/KLF7-mediated Wnt/beta-catenin pathway.

Authors:  Jianwu Long; Longfei Liu; Xuefeng Yang; Xiaojun Zhou; Xianzhou Lu; Lei Qin
Journal:  Hum Cell       Date:  2022-10-15       Impact factor: 4.374

2.  Bioinformatics analysis of key biomarkers and potential molecular mechanisms in hepatocellular carcinoma induced by hepatitis B virus.

Authors:  Zhe Li; Jingyong Xu; Hongyuan Cui; Jinghai Song; Jian Chen; Junmin Wei
Journal:  Medicine (Baltimore)       Date:  2020-05       Impact factor: 1.889

3.  Clinical application of combined laparoscopic surgery in the treatment of primary hepatocellular carcinoma with portal hypertension: a report of 16 cases.

Authors:  Peng Guo; Shengtao Liao; Jianwei Li; Shuguo Zheng
Journal:  Transl Cancer Res       Date:  2019-02       Impact factor: 1.241

  3 in total

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