D G O'Neill1, J Case1, A K Boag2, D B Church3, P D McGreevy4, P C Thomson4, D C Brodbelt1. 1. Pathobiology and Population Sciences, The Royal Veterinary College, Hatfield, Herts AL9 7TA, UK. 2. Vets Now Ltd., Castle Riggs, Dunfermline KY11 8SG, UK. 3. Clinical Sciences and Services, The Royal Veterinary College, Hatfield, Herts AL9 7TA, UK. 4. Faculty of Veterinary Science, The University of Sydney, Sydney, New South Wales 2006, Australia.
Abstract
OBJECTIVE: To report prevalence, risk factors and clinical outcomes for presumptive gastric dilation-volvulus diagnosed among an emergency-care population of UK dogs. METHODS: The study used a cross-sectional design using emergency-care veterinary clinical records from the VetCompass Programme spanning September 1, 2012 to February 28, 2014 and risk factor analysis using multivariable logistic regression modelling. RESULTS: The study population comprised 77,088 dogs attending 50 Vets Now clinics. Overall, 492 dogs had presumptive gastric dilation-volvulus diagnoses, giving a prevalence of 0·64% (95% Confidence interval: 0·58 to 0·70%). Compared with cross-bred dogs, breeds with the highest odds ratios for the diagnosis of presumptive gastric dilation-volvulus were the great Dane (odds ratio: 114·3, 95% Confidence interval 55·1 to 237·1, P<0·001), akita (odds ratio: 84·4, 95% Confidence interval 33·6 to 211·9, P<0·001) and dogue de Bordeaux (odds ratio: 82·9, 95% Confidence interval 39·0 to 176·3, P<0·001). Odds increased as dogs aged up to 12 years and neutered male dogs had 1·3 (95% Confidence interval 1·0 to 1·8, P=0·041) times the odds compared with entire females. Of the cases that were presented alive, 49·7% survived to discharge overall, but 79·3% of surgical cases survived to discharge. CLINICAL SIGNIFICANCE: Approximately 80% of surgically managed cases survived to discharge. Certain large breeds were highly predisposed.
OBJECTIVE: To report prevalence, risk factors and clinical outcomes for presumptive gastric dilation-volvulus diagnosed among an emergency-care population of UK dogs. METHODS: The study used a cross-sectional design using emergency-care veterinary clinical records from the VetCompass Programme spanning September 1, 2012 to February 28, 2014 and risk factor analysis using multivariable logistic regression modelling. RESULTS: The study population comprised 77,088 dogs attending 50 Vets Now clinics. Overall, 492 dogs had presumptive gastric dilation-volvulus diagnoses, giving a prevalence of 0·64% (95% Confidence interval: 0·58 to 0·70%). Compared with cross-bred dogs, breeds with the highest odds ratios for the diagnosis of presumptive gastric dilation-volvulus were the great Dane (odds ratio: 114·3, 95% Confidence interval 55·1 to 237·1, P<0·001), akita (odds ratio: 84·4, 95% Confidence interval 33·6 to 211·9, P<0·001) and dogue de Bordeaux (odds ratio: 82·9, 95% Confidence interval 39·0 to 176·3, P<0·001). Odds increased as dogs aged up to 12 years and neutered male dogs had 1·3 (95% Confidence interval 1·0 to 1·8, P=0·041) times the odds compared with entire females. Of the cases that were presented alive, 49·7% survived to discharge overall, but 79·3% of surgical cases survived to discharge. CLINICAL SIGNIFICANCE: Approximately 80% of surgically managed cases survived to discharge. Certain large breeds were highly predisposed.
Authors: Paul McGreevy; Peter Thomson; Navneet K Dhand; David Raubenheimer; Sophie Masters; Caroline S Mansfield; Timothy Baldwin; Ricardo J Soares Magalhaes; Jacquie Rand; Peter Hill; Anne Peaston; James Gilkerson; Martin Combs; Shane Raidal; Peter Irwin; Peter Irons; Richard Squires; David Brodbelt; Jeremy Hammond Journal: Animals (Basel) Date: 2017-09-26 Impact factor: 2.752
Authors: Ignazio S Piras; Nieves Perdigones; Victoria Zismann; Natalia Briones; Salvatore Facista; José Luis Rivera; Elizabeth Rozanski; Cheryl A London; William P D Hendricks Journal: Genes (Basel) Date: 2020-11-05 Impact factor: 4.096