Conor P Kerley1. 1. Physicians Committee for Responsible Medicine, 5100 Wisconsin Avenue, N.W. Ste. 400, Washington, District of Columbia, USA.
Abstract
PURPOSE OF REVIEW: Early interventional trials reported improvements in cardiac and exercise outcomes with inorganic nitrate ingestion. The current review aims to provide a brief update of recent evidence regarding ergogenic and cardiovascular effects of dietary nitrate and practical recommendations. RECENT FINDINGS: Recent evidence has been inconsistent and questions remain regarding effective dose, duration, and source of nitrate and cohorts likely to benefit. Dietary nitrate may be most relevant to those with vascular/metabolic impairments, those engaging in short-term, intense exercise, deconditioned individuals, and those with a low dietary nitrate intake. SUMMARY: The evidence for cardiovascular/exercise benefit is plausible but inconsistent. However, dietary nitrate, in contrast to pharmacological nitrate, has a high benefit-risk ratio. Although nitrate supplementation has grown in popularity, it is suggested that increased green vegetables consumption may provide similar/superior benefits to nitrate supplementation in a cheaper, safer, and potentially tastier context.
PURPOSE OF REVIEW: Early interventional trials reported improvements in cardiac and exercise outcomes with inorganic nitrate ingestion. The current review aims to provide a brief update of recent evidence regarding ergogenic and cardiovascular effects of dietary nitrate and practical recommendations. RECENT FINDINGS: Recent evidence has been inconsistent and questions remain regarding effective dose, duration, and source of nitrate and cohorts likely to benefit. Dietary nitrate may be most relevant to those with vascular/metabolic impairments, those engaging in short-term, intense exercise, deconditioned individuals, and those with a low dietary nitrate intake. SUMMARY: The evidence for cardiovascular/exercise benefit is plausible but inconsistent. However, dietary nitrate, in contrast to pharmacological nitrate, has a high benefit-risk ratio. Although nitrate supplementation has grown in popularity, it is suggested that increased green vegetables consumption may provide similar/superior benefits to nitrate supplementation in a cheaper, safer, and potentially tastier context.
Authors: Ágnes D de Lima Bezerra; Eduardo C Costa; Daniela A Pacheco; Daniel C Souza; Luiz F Farias-Junior; Raphael M Ritti-Dia; Gisele B Grigolo; Paulo I H de Bittencourt Júnior; Mauricio Krause; Ana P T Fayh Journal: J Sports Sci Med Date: 2019-02-11 Impact factor: 2.988
Authors: Eduardo Cuenca; Pablo Jodra; Alberto Pérez-López; Liliana G González-Rodríguez; Sandro Fernandes da Silva; Pablo Veiga-Herreros; Raúl Domínguez Journal: Nutrients Date: 2018-09-04 Impact factor: 5.717