Marta Baczyńska-Strzecha1, Jarosław Kalinka2. 1. Medical University in Lodz, Łódź, Poland (Department of Perinatology, 1st Chair of Obstetrics and Gynecology). m.baczynska@onet.eu. 2. Medical University in Lodz, Łódź, Poland (Department of Perinatology, 1st Chair of Obstetrics and Gynecology). j.kalinka@csk.am.lodz.pl.
Abstract
OBJECTIVES: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. MATERIAL AND METHODS: 25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. RESULTS: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% - in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86-7.15, p = 0.094). CONCLUSIONS: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933-941. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.
OBJECTIVES: Aim of this project is determination of the correlation between the level of vitamin D in blood serum and duration of pregnancy in population in central Poland. MATERIAL AND METHODS:25-Hydroxyvitamin D (25(OH)D) level was determined in blood serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history of each patient was recorded. The history included: general medical history, data regarding the course of pregnancy and information about health-related behavior that could influence vitamin D concentration. Two hundred-and-one Caucasian women at childbirth were qualified into the study. The study group was divided into 2 parts: 100 patients who had a spontaneous premature birth and 101 patients who had birth at full term. RESULTS: Vitamin D deficiency (< 30 ng/ml) was very common for both groups (69.6% of patients in the premature group and 72% - in the control group). Patients who had a premature birth had severe vitamin D deficiency (less than 10 ng/ml) more often than in the control group (34% vs. 14.2%, p = 0.001). Severe vitamin D deficiency increased the risk of premature birth but the association was not statistically significant in the multivariate regression model (odds ratio (OR) = 2.47, 95% confidence interval (CI): 0.86-7.15, p = 0.094). CONCLUSIONS: Severe vitamin D deficiency (< 10 ng/ml) may be the factor increasing the risk of preterm birth. Int J Occup Med Environ Health 2017;30(6):933-941. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.
Authors: Regina Wierzejska; Mirosław Jarosz; Włodzimierz Sawicki; Michał Bachanek; Magdalena Siuba-Strzelińska Journal: Int J Environ Res Public Health Date: 2017-09-26 Impact factor: 3.390
Authors: Huijuan Li; Jing Ma; Runzhi Huang; Yuhua Wen; Guanghui Liu; Miao Xuan; Ling Yang; Jun Yang; Lige Song Journal: Arch Public Health Date: 2020-06-04
Authors: Michał Ciebiera; Cezary Wojtyła; Krzysztof Łukaszuk; Magdalena Zgliczyńska; Kornelia Zaręba; Wojciech Rawski; Grzegorz Jakiel Journal: Arch Med Sci Date: 2019-01-30 Impact factor: 3.318