Fady F Abd El-Malek1, Amany S Yousef2, Samy A El-Assar2. 1. Department of Microbiology, Faculty of Science, Alexandria University, Alexandria, Egypt. Electronic address: fadymicro@yahoo.com. 2. Department of Microbiology, Faculty of Science, Alexandria University, Alexandria, Egypt.
Abstract
OBJECTIVES: Chronic wound infections can be effectively treated using hydrogel loaded with an extract from manuka honey. METHODS: This study was performed on bacterial isolates from patients with infected wounds at Alexandria Main University Hospital (Alexandria, Egypt). Isolates were exposed to hydrogel sheets composed of chitosan and gelatin and loaded with a new formula from manuka honey. RESULTS: The results illustrate the antibacterial activity of the formula extracted from manuka honey against Staphylococcus aureus, Streptococcus pyogenes, Acinetobacter baumannii, Pseudomonas aeruginosa and Proteus mirabilis. Screening of the hydrogel by electron microscopy showed the ultrastructure of the gel. CONCLUSIONS: A hydrogel sheet composed of chitosan and gelatin loaded with a new formula extracted from manuka honey can be used as a dressing for chronic infected wounds.
OBJECTIVES: Chronic wound infections can be effectively treated using hydrogel loaded with an extract from manuka honey. METHODS: This study was performed on bacterial isolates from patients with infected wounds at Alexandria Main University Hospital (Alexandria, Egypt). Isolates were exposed to hydrogel sheets composed of chitosan and gelatin and loaded with a new formula from manuka honey. RESULTS: The results illustrate the antibacterial activity of the formula extracted from manuka honey against Staphylococcus aureus, Streptococcus pyogenes, Acinetobacter baumannii, Pseudomonas aeruginosa and Proteus mirabilis. Screening of the hydrogel by electron microscopy showed the ultrastructure of the gel. CONCLUSIONS: A hydrogel sheet composed of chitosan and gelatin loaded with a new formula extracted from manuka honey can be used as a dressing for chronic infected wounds.
Authors: Annachiara Scalzone; Giorgia Cerqueni; Maria A Bonifacio; Michele Pistillo; Stefania Cometa; Monica Mattioli Belmonte; Xiao N Wang; Kenny Dalgarno; Ana M Ferreira; Elvira De Giglio; Piergiorgio Gentile Journal: Mater Today Bio Date: 2022-05-13
Authors: Carlos Martinez-Armenta; María Carmen Camacho-Rea; Gabriela Angélica Martínez-Nava; Rocio Espinosa-Velázquez; Carlos Pineda; Luis Enrique Gomez-Quiroz; Alberto López-Reyes Journal: Front Pharmacol Date: 2021-04-21 Impact factor: 5.810
Authors: Ayman M Mousa; Khaled S Allemailem; Fahad A Alhumaydhi; Faris Alrumaihi; Ahmad Almatroudi; Mohammad Aljasir; Ameen S S Alwashmi; Osamah Al Rugaie; Khaled E A Soliman; Abdullah S M Aljohani; Waleed Al Abdulmonem; Ahmed A Ahmed; Arif Khan; Masood A Khan; Naif AlSuhaymi; Mahdi H Alsugoor; Wafa Abdullah Al-Megrin; Abulmaaty M Elsayed Journal: Evid Based Complement Alternat Med Date: 2022-03-17 Impact factor: 2.629