| Literature DB >> 28830088 |
Jennifer Mahony1,2, Christian Cambillau3,4, Douwe van Sinderen1,2.
Abstract
Bacteriophage infection of lactic acid bacteria (LAB) is one of the most significant causes of inconsistencies in the manufacture of fermented foods, affecting production schedules and organoleptic properties of the final product. Consequently, LAB phages, and particularly those infecting Lactococcus lactis, have been the focus of intensive research efforts. During the past decade, multidisciplinary scientific approaches have uncovered molecular details on the exquisite process of how a lactococcal phage recognises and binds to its host. Such approaches have incorporated genomic/molecular analyses and their partnership with phage structural analysis and host cell wall biochemical studies are discussed in this review, which will also provide our views on future directions of this research field. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.Entities:
Keywords: Lactococcus; bacteriophage; carbohydrate; cell wall; dairy; protein; receptor
Mesh:
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Year: 2017 PMID: 28830088 DOI: 10.1093/femsre/fux019
Source DB: PubMed Journal: FEMS Microbiol Rev ISSN: 0168-6445 Impact factor: 16.408