Literature DB >> 28828702

[Intoxication with psychotropic drugs].

R Bellmann1, M Joannidis2.   

Abstract

Psychotropic drugs are medications that are indicated for treatment of psychiatric disorders. Attempted suicide is the major reason for intoxication but inadvertent overdosing may also occur. Other psychotropic agents are taken because of their stimulating and hallucinogenic effects and many have a high addictive potential. Poisoning is usually due to accidental overdosing. For treatment of benzodiazepine and opioid intoxication, flumazenil and naloxone, respectively, are used as specific antagonists. For intoxication by tricyclic antidepressants, sodium bicarbonate is the treatment of choice. It can also be administered for poisoning caused by selective serotonin re-uptake inhibitors and neuroleptics, in cases of cardiotoxicity. Torsades de pointes can be terminated with defibrillation and intravenous magnesium. Symptomatic treatment is performed for intoxications caused by analeptics or hallucinogens. Beta blockers must be avoided in cocaine and amphetamine poisoning.

Entities:  

Keywords:  Designer drugs; Drug abuse; Drug overdose; Psychotropic drugs; Street drugs

Mesh:

Substances:

Year:  2017        PMID: 28828702     DOI: 10.1007/s00063-017-0323-8

Source DB:  PubMed          Journal:  Med Klin Intensivmed Notfmed        ISSN: 2193-6218            Impact factor:   0.840


  36 in total

Review 1.  Speculations on difference between tricyclic and selective serotonin reuptake inhibitor antidepressants on their cardiac effects. Is there any?

Authors:  P Pacher; Z Ungvari; P P Nanasi; S Furst; V Kecskemeti
Journal:  Curr Med Chem       Date:  1999-06       Impact factor: 4.530

Review 2.  Part 12: cardiac arrest in special situations: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Authors:  Terry L Vanden Hoek; Laurie J Morrison; Michael Shuster; Michael Donnino; Elizabeth Sinz; Eric J Lavonas; Farida M Jeejeebhoy; Andrea Gabrielli
Journal:  Circulation       Date:  2010-11-02       Impact factor: 29.690

Review 3.  Bath salts, mephedrone, and methylenedioxypyrovalerone as emerging illicit drugs that will need targeted therapeutic intervention.

Authors:  Richard A Glennon
Journal:  Adv Pharmacol       Date:  2014

4.  Assessment of GABA(A)benzodiazepine receptor (GBzR) sensitivity in patients on benzodiazepines.

Authors:  J Potokar; N Coupland; S Wilson; A Rich; D Nutt
Journal:  Psychopharmacology (Berl)       Date:  1999-09       Impact factor: 4.530

Review 5.  Pharmacokinetics of cannabinoids.

Authors:  Iain J McGilveray
Journal:  Pain Res Manag       Date:  2005       Impact factor: 3.037

6.  [Acute poisoning in adults].

Authors:  L Weidhase; H Hentschel; L Mende; G Schulze; S Petros
Journal:  Internist (Berl)       Date:  2014-03       Impact factor: 0.743

Review 7.  Cocaine-associated intracranial hemorrhage: absence of vasculitis in 14 cases.

Authors:  S K Aggarwal; V Williams; S R Levine; B J Cassin; J H Garcia
Journal:  Neurology       Date:  1996-06       Impact factor: 9.910

8.  Effect of hypertonic sodium bicarbonate in the treatment of moderate-to-severe cyclic antidepressant overdose.

Authors:  J R Hoffman; S R Votey; M Bayer; L Silver
Journal:  Am J Emerg Med       Date:  1993-07       Impact factor: 2.469

9.  Hemoperfusion in the treatment of acute clozapine intoxication in China.

Authors:  Jia-Li He; Yu-Tao Xiang; Wen-Biao Li; Zhuo-Ji Cai; Gabor Sandor Ungvari
Journal:  J Clin Psychopharmacol       Date:  2007-12       Impact factor: 3.153

Review 10.  SSRI safety in overdose.

Authors:  J T Barbey; S P Roose
Journal:  J Clin Psychiatry       Date:  1998       Impact factor: 4.384

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  1 in total

Review 1.  [Tapering of antidementia drugs, antidepressants and antipsychotics in elderly patients : When possible, when not?]

Authors:  K Hager; T Temps; O Krause
Journal:  Med Klin Intensivmed Notfmed       Date:  2018-06-06       Impact factor: 0.840

  1 in total

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