Literature DB >> 28828673

Production and Characterization of Extracellular Vesicles in Malaria.

Smart Mbagwu1, Michael Walch1, Luis Filgueira1, Pierre-Yves Mantel2.   

Abstract

Growing attention is drawn toward the role of extracellular vesicles (EVs) in infectious diseases. EVs, which are small vesicles released by cells, are involved in cellular communication, immune regulation, and pathogenesis. EVs act as messenger carrying functional cargoes, including RNA, DNA, lipids and proteins from a donor cell to regulate the function of a recipient cell. In malaria, EVs play a key role in regulating the progression from the blood to the transmission stage by promoting the switch between asexual and sexual stages that are taken up by mosquitoes. In addition to their role in parasite communication, EVs modulate the immune system and regulate endothelial cell function.In this chapter, we describe protocols to isolate, purify and characterize EVs derived from Plasmodium falciparum infected red blood cell culture.

Entities:  

Keywords:  Cellular communication; Extracellular vesicles; Malaria; Plasmodium falciparu m

Mesh：

Year:  2017        PMID： 28828673     DOI： 10.1007/978-1-4939-7253-1_31

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  6 in total

1.  Plasmodium falciparum sexual parasites develop in human erythroblasts and affect erythropoiesis.

Authors:  Gaëlle Neveu; Cyrielle Richard; Florian Dupuy; Prativa Behera; Fiona Volpe; Pradeep Annamalai Subramani; Benjamin Marcel-Zerrougui; Patrice Vallin; Muriel Andrieu; Aruna Mukti Minz; Nabih Azar; Rafael M Martins; Audrey Lorthiois; Florence Gazeau; José-Juan Lopez-Rubio; Dominique Mazier; Amanda K A Silva; Sanghamitra Satpathi; Samuel C Wassmer; Frédérique Verdier; Catherine Lavazec
Journal:  Blood       Date:  2020-09-17       Impact factor: 22.113

2.  Validation of Effective Extracellular Vesicles Isolation Methods Adapted to Field Studies in Malaria Endemic Regions.

Authors:  Matteo Zoia; Bibin Yesodha Subramanian; Klara Kristin Eriksson; Meera Sruthi Ravi; Shekoofeh Yaghmaei; Isabelle Fellay; Brigitte Scolari; Michael Walch; Pierre-Yves Mantel
Journal:  Front Cell Dev Biol       Date:  2022-05-16

3.  Evaluation of Extracellular Vesicle Function During Malaria Infection.

Authors:  María Andrea Hernández-Castañeda; Smart Mbagwu; Kehinde Adebayo Babatunde; Michael Walch; Luis Filgueira; Pierre-Yves Mantel
Journal:  J Vis Exp       Date:  2018-02-14       Impact factor: 1.355

4.  Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock.

Authors:  Duaa A Dakhlallah; Jon Wisler; Marieta Gencheva; Candice M Brown; Erin R Leatherman; Kanhaiya Singh; Kathy Brundage; Todd Karsies; Ahmad Dakhlallah; Kenneth W Witwer; Chandan K Sen; Timothy D Eubank; Clay B Marsh
Journal:  J Extracell Vesicles       Date:  2019-09-28

5.  Human Microglia Respond to Malaria-Induced Extracellular Vesicles.

Authors:  Smart Ikechukwu Mbagwu; Nils Lannes; Michael Walch; Luis Filgueira; Pierre-Yves Mantel
Journal:  Pathogens       Date:  2019-12-24

Review 6.  Role of Extracellular Vesicles in Cellular Cross Talk in Malaria.

Authors:  Kehinde Adebayo Babatunde; Bibin Yesodha Subramanian; Ambroise Dioum Ahouidi; Paola Martinez Murillo; Michael Walch; Pierre-Yves Mantel
Journal:  Front Immunol       Date:  2020-01-31       Impact factor: 7.561
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.